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Polycystic Ovarian Syndrome [PCOS]-A Case Study with
Constitutional Homoeopathic Treatment
1
Dr.Kailas Dharavath.,
2
Dr. Sarvabhotla Swathi Sri Varsha
1
Asst. Prof. Dept. of Hom. Materia Medica, Hamsa Homeopathy Medical College Hospital & Research
Centre. Ksheerasagar (V), Mulugu (M), Siddipet Dist Telagana State
2
PG Junior Resident Dept. of Hom.Materia Medica Hamsa Homeopathy medical college, Hospital &
Research Centre
*Correspondence Author
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
ABSTRACT
Background:
Polycystic Ovarian Syndrome (PCOS) is a multifactorial endocrine disorder affecting reproductive,
metabolic, and emotional health in women of reproductive age. Conventional treatments often provide
symptomatic relief but may not address the individual constitution. Homeopathy offers a holistic approach,
prescribing on the basis of totality of symptoms.
Objective:
To present a case of PCOS in a 30-year-old female successfully managed with individualized constitutional
homeopathic treatment using Pulsatilla.
Methods:
A detailed case history was taken, including physical generals, mental generals, and life space information.
Investigations such as ultrasonography confirmed bilateral polycystic ovarian morphology. Repertorial
analysis was carried out using Zomeo Pro software. Pulsatilla was selected as the constitutional similimum
and prescribed in varying potencies, along with placebo.
Results:
Within three months of treatment, the patient experienced normalization of menstrual cycles and resolution of
dysmenorrhoea. Follow-up ultrasonography revealed normal ovarian morphology. Continued follow-up over
several months showed sustained improvement in menstrual regularity, emotional stability, and general well-
being.
Conclusion:
This case demonstrates the potential role of individualized homeopathic treatment in managing PCOS.
Pulsatilla, prescribed on the basis of totality of symptoms, not only restored menstrual function but also
improved mental and emotional health.
Keywords: Polycystic Ovary Syndrome (PCOS), Oligomenorrhoea, Homeopathy, General management,
Constitutional Treatment, Pulsatilla.
INTRODUCTION
Polycystic Ovarian Disease (PCOD) is a common endocrine disorder of reproductive-age women, marked by
an imbalance in female sex hormones and the presence of multiple ovarian cysts. It can progress into
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Polycystic Ovarian Syndrome (PCOS), a multisystem condition associated with reproductive, metabolic, and
emotional disturbances.
Key features include irregular or absent menses, infertility, obesity, acne, hirsutism, and androgen excess. If
untreated, PCOS predisposes to type 2 diabetes, cardiovascular disease, hypertension, and certain cancers.
Diagnosis is based on history, examination, hormone assays, and ultrasound. Globally, ~18% of women are
affected, with many undiagnosed. The condition, first described by Stein and Leventhal in 1935, is
sometimes termed “ovarian androgen excess.
5
Aetiology & Pathogenesis
The exact cause of PCOS is unclear but involves genetic, environmental, and lifestyle factors. Sedentary
habits, stress, and dietary influences contribute, while familial and genetic associations (e.g., CYP21
mutation) have been noted. Insulin resistance and hyperinsulinemia are central mechanisms, promoting
ovarian androgen production and anovulation. Obesity (seen in 5070% of cases) exacerbates insulin
resistance through adipose-derived cytokines and hormones. Raised LH levels, altered hypothalamic-
pituitary-ovarian axis function, and adrenal factors also play roles.
Pathology:
Both ovaries are typically enlarged with a thickened tunica albuginea. On ultrasound, ≥12 small peripheral
cysts (2–9 mm) give the classic string of pearlsappearance. Theca-cell and stromal hyperplasia contribute
to increased ovarian volume (>10 cm³).
Clinical Features Of Pcos:
1
CLINICAL FEATURES
HORMAL
SEQUALAE
Young Woman
E2 levels
Diabetes(15%)
Central obesity
LH levels
Cardiovascular Disease
BMI>30kg/cm2
FSH/LH ratio
Lipidaemia’s
Waist line>88cm
Androgens
Hypertension
Oligomenorrhoea, amenorrhoea
Testosterone, epi-androstenedione,
dehydroepiandrosterone.
Endometrial cancer
Infertility
17- alpha-hydroxyprogesterone> 300ng/
dl
Breast cancer
Hirsutism
Testosterone>2ng/ml
Premature ovarian
failure following
surgery
Acanthosis nigricans due to insulin
resistance; thick pigmented skin over
the nape of the neck, inner thigh and
axilla.
Prolactin ,
(SHBG)↓Sex hormone-binding globulin
Most androgen come from ovary
↓E2 /oestrone (E1 ) ratio
fasting insulin>10miu/l
F. glucose/insulin ratio<4.5
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Conventional Management
Treatment In Women With Pcos-
8
Obesity and Metabolic syndrome
Diet, Exercise, change of lifestyle Metformin
Subfertility
Ovulation induction: Letrozole, metformin, gonadotropins
AUB
Progestins, COCs
Body Hair
Antiandrogens, COCs
(COCs-combined oral contraceptives)
Lifestyle modificationsdietary changes, physical activity, and behavioral interventionsare crucial in
managing PCOS by addressing metabolic and reproductive issues. RCTs show that low-GI foods, calorie
restriction, high-fiber, ketogenic, Mediterranean, omega-3/antioxidant-rich, and anti-inflammatory diets
improve insulin sensitivity, hormonal balance, and PCOS symptoms. Among these, the DASH and low-GI
diets are most effective, reducing insulin resistance, androgen levels, and menstrual irregularities. Regular
exercise, especially aerobic and resistance training, supports weight loss, glucose regulation, hormonal
balance, and better quality of life. Aerobic exercise is particularly effective, with both continuous (CAT) and
intermittent (IAT) training improving body composition, hyperandrogenism, and quality of life in PCOS
women.
9
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Homoeopathic Therapeutics:
Indications of few Homeopathic medicines for PCOS are given below:
1. Sepia Sepia is One of the most important uterine remedies. Sepia affects the venous circulation
particularly of the female pelvic organs and of GIT tract. It acts specially on the portal system with venous
congestion. Uterus prolapsed. Weakness, anaemic, bearing-down Sensation, especially in women, upon whose
organism it has most pronounced effect. Pains goes down to back, easily chilly. Amelioration by sitting with
legs crossed, by exercise, dancing. Menses too late and irregular and scanty, early and profuse, sharp clutching
pains. Violent stitches upward in the vagina, from uterus to umbilicus. Prolapse of uterus and vagina.
Irritability, alternating with indifference. Indifference. Takes pleasure in teasing others. Sad over her health
and domestic affairs. Aversion to family to those loved best to sympathy to company, yet fear of alone.
2-Natrum Mur: Nat-m. women is very sensitive, Anaemic, emaciated, Ill effects of grief, anger, guilt,
disappointment, fright, fit of passion, loss of fluids, Sunlight. Menses irregular, profuse, Suppressed, and
Bearing down pain in abdomen. Nat-m. covers the ailments from grief, anger, disappointed love and fright.
Natrum Mur suited to Depressed and introverted. Consolation aggravates. Fear of being rejected, fear and
anxiety.
3- Pulsatilla: Dr. Hahnemann gives the Pulsatilla patients disposition and temperament: "A timid, mild and
yielding disposition, weeping disposition with a tendency to inward grief, weeps when talking and silent
peevishness, contradictory mood. Pulsatilla acts when there is a disposition to chilliness and thirstlessness. It is
suitable for females when there is delay menses. Menstrual cycle too late, scanty, dark, thick, clotted,
changeable, intermittent, painful, flow intermits, pain in back aggravates by lying down on left side or on
painless side. Better in open air.
4-Calcarea carb: Calcarea carb patient is fair, fatty, flabby and profuse perspiring. Painful swelling in the
breasts before the menstrual flow begins. Suppressed menses after working in water. Bearing-down sensation.
Fibroids and cysts. Ovarian or uterine pains, right sided, extending down thighs, aggravates on reading or
writing. Cutting pain in uterus during menstruation, worse from mental exertion or physical exertion. Better by
lying on painful side. Uterine polypi.
5-Thuja occidentalis: Thuja is the remedy for exuberant, soft, fungoid tissue, polyps. Great prostration and
rapid emaciation. The patient is exhausted and soft body feels thin and delicate, fragile. Discharges are foul,
acrid, musty or of sweetish Odor. Severe pain in left ovary and left inguinal region. Menstrual flow scanty,
retarded. Uterine polypi. Leucorrhoea thick greenish. Profuse perspiration before menses.
6-Kali carb: Kali carb suited to persons of soft tissues with tendency to be fat. Kali-c. is suited to the obese,
lax tissue. Kali carb patients’ pain is sharp and cutting, pain better by motion. Fear of death, future ghosts,
Anxiety with fear when alone. Anxiety about health. Manses early, profuse, or too late, and scanty, Pains from
back extend through gluteal muscles, with cutting pain in abdomen. Uterine hemorrhage. Pain relieved by
sitting and pressure.
7- Silicea: Silicea remedy suited to yielding, excitable, Anxious, nervous, weeping mood and sensitive to all
impressions. Sensitive to noise, want of self-confidence, fear of failure. Ailments from anticipation. A milky,
acrid leucorrhoea discharge, Itching of vulva and vagina. Bleeding between menstrual periods. Profuse menses
with paroxysms of icy coldness over whole body. Vaginal cyst. Complaints aggravates from washing during
menses.
7
Case Report
A 30-year-old married female presented to the Department of Homeopathic Materia Medica, Hamsa
Homeopathy Medical College, Hospital & Research Centre, ksheerasagar (V), Siddipet (D), on 10th January
2025, Reg.no- 25/4129 with complaints of scanty, painful menses associated with brownish clots for the past 2
years. She had conceived once, three months after marriage, but experienced a spontaneous abortion. She had
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been advised in vitro fertilization (IVF) by a gynecologist, which was financially unfeasible, leading to
significant anxiety regarding infertility
Past History: Recurrent cold attacks (on and off) K/C/O- B/L-PCOD
Family History: Father died due to TB.
Physical Generals:
SLEEP- Disturbed, midnight after 2am-5am.
DREAMS- As if she is pregnant, holding child.
THIRST-2-3 litres/day
APPETITE-Moderate
DESIRES-Sour food
URINE-Clear
SWEAT-Scanty
STOOL-Regular and satisfactory
CONSTITUTION- Lean, thin, short stature with wheat complexion.
THERMALS- Towards Chilly
MENSES- LMP 16/12/24, 3 days flow, scanty, dysmenorrhoea, clots brownish colour, menarche at the age of
13 years.
Life Space Investigation:
patient hails from middle class family, studied up to 12th std. she got married at the age of 19 years and its
consanguineous marriage. Conceived 3months after marriage and got aborted. Then she consulted a DGO and
they suggested IVF which is very expensive, from then she started worrying about children. she is very much
attached to her father; he died with TB. she runes a bangle store. she desires company with family, husband.
changeability in mood with offended easily and consolation amelioration. she worries about her husband that
something bad is going to happen and also suspicious, possessive in nature. She doesn’t allow him to talk with
others even in family relations, because he often gives money and other things to his family. she often checks
his phone call history for any female calls or messages from office colleagues.
Mental Generals:
Grief-death of loved one -father; Religious affections; Anxiety about health and future
Consolation amelioration; Easily offended; Fear of ghost; Fear of dark
Weeping tendency; Suspicious nature, Jealousy.
General Physical Examination:
GENERAL APPEARANCE-GOOD.
GENERAL BUILT AND NUTRITION-Moderate.
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GAIT-Biphasic Bipedalic gait. CLUBBING No PALLOR- no.
ICTERUS- No CYANOSIS- no.
Oedema- No NAILS-No discoloration, healthy. LYMPHADENOPATHY-no.
WEIGHT:50kgs. HEIGHT-5.0', BMI-21.5kg/m²
Vitals:
PULSE:86beats/min. BLOODPRESSURE:130/80mmofhg.
RESPIRATORYRATE:16breaths/min. TEMPERATURE-Afebrile.
Systemic Examination:
Respiratory-Vesicular breath sounds heard
CVS-S1,S2 sounds heard normal.
GI-Bowel sounds normal.
Locomotor-Appearance and movements normal.
CNS-conscious and well oriented with good memory.
Integumentary and Glands- no acanthosis nigricans.
Investigations: [Performed]
07/08/23 and 16/01/25;
Left small renal calculi.
Small anterior uterine wall fibroid.
PCOD patter of both ovaries.
Investigations Suggested:
USG Abdomen Suggested.
Provisional Diagnosis:
B/L Polycystic Ovarian Disease [PCOD]
Totality Of Symptoms:
Religious Affections; Anxiety about health; Grief ; Fear of dark; Fear of ghost
Suspicious, mistrustfulness; Jealousy; Sympathetic; Dreams of being pregnant
Consolation >; Weeping tendency; Offended easily; Desires sour and acid foods
Constitution-lean personality; Menses clotted, brown colour; Dysmenorrhoea
Polycystic ovarian disease; 3rd month abortion.
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Repertorization Analysis:
Puls 66/19, Lach 54/17, Sulph 54/17, Lyco 53/19,
Ars 52/18, Ign52/16, Phos 50/19, Nux50/17, Nat-m48/17,
Caust48/16, Calc47/18, Nit-ac44/16, Sep43/17, Rhus-tox 43/15.
Repertorial Sheet:
6
Medicine Prescribed: 1. Pulsatilla 200/2doses. BID
2. Placebo /1week. TID
Remedy Selected: Pulsatilla
Pulsatilla weeps easily, fears to dark places and ghosts. likes sympathy and consolation amelioration, religious,
clotted and painful menses[dysmenorrhoea]. mistrustful, anxious about health, easily offended, suspicious,
craves acids, fulness after eating, easy satiety.
234
Potency: According to the susceptibility of the patient and intensity of the disease 200 is selected.
Dosage: According to severity of disease dosage is selected.
Followups:
FOLLOWUP
PRESCRIPTION
LMP-18/1/2025 -3days flow, no clots, no
leucorrhoea,Dysmenorrhoea +, Suspicious++, Anxiety++.
Pulsatilla 1m 1 dose
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LMP- 17/2/2025- 3 days flow, no clots ,no leucorrhoea, no
pain during or before menses.
USG- 21-2-25
IMPRESSION-Normal Study.
Placebo/1month.
LMP-18/03/25- 3 days flow
Bloating of abdomen and watery discharge before menses
with increased appetite.
Suspicious and anxiety+ decreased but slightly present.
Pulsatilla 1m 1dose
Before Treatment:
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After Treatment:
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CONCLUSION
As the PCOS is a multi-faceted problem with reproductive, endocrine and metabolic dysfunction. The lifestyle
modification and counselling is considered to be the first line of treatment which is effective when we consider
the constitution, mental and physical generals. Cases can be treated successfully by homoeopathy in order to
get cure. Special diet is a very important aspect of PCOS care. Replacing manufactured carbohydrate products
with whole grains, fruits and vegetables can help to reduce insulin response. The diet also should include
enough protein to control the amount of sugar in the blood. Exercise also can help to maintain the insulin level
and weight. In above explained case, her menstrual irregularity and other associated symptoms became normal
with pulsatilla in just 2 months, still under treatment including her husband with oligospermia. This shows,
how effective homoeopathy is in treating such lifestyle disorders in a short course of time. Homoeopathic
Treatment based on symptoms similarity (Totality of symptoms). For selection of remedy, a detailed case
taking and repertorization are necessary.
5
ACKNOWLEDGEMENT
The authors express their sincere gratitude to Dr. Umesh Akkaladevi, Director; Dr. Nurus Saher Khan,
Principal; and Dr. Srinivas Babu Kathi, Medical Superintendent. Dr. B. Ramesh, HOD. Dr. P V Sai Santosh
kiran, Associate Professor. Dr. V. Hema Latha Assistant Professor, and Dr. Arunima, Dr. Sindhu PG part I,
Department of Homeopathic Materia Medica, Hamsa Homoeopathy Medical College, Hospital & Research
Centre, Siddipet District, Telangana, for their valuable suggestions and continuous support.
Conflict Of Interest: Authors Declare No Conflict of Interest.
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Dr .Kailas Dharavath,
Asst. Prof. Dept. of Hom.Materia Medica ,
Hamsa Homeopathy Medical College
Hospital & Research Centre.
Ksheerasagar(V), Mulugu(M), Siddipet Dist.
Dr .Sarvabhotla Swathi Sri Varsha,
PG Junior Resident
Dept. of Hom.Materia Medica
Hamsa Homeopathy medical college,
Hospital & Research Centre.