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ISSN No. 2454-6186 | DOI: 10.47772/IJRISS | Volume IX Issue X October 2025
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Comparative Analysis of Profitability Performance in the Pharmaceutical
Industry of Bangladesh: Pre and Post COVID-19
Md. Rizwan Hassan
Associate Professor Department of Business Administration International Islamic University Chittagong
DOI:
https://dx.doi.org/10.47772/IJRISS.2025.910000765
Received: 28 October 2025; Accepted: 05 November 2025; Published: 24 November 2025
ABSTRACT
Covid-19 was emerged as pandemic in the entire world during 2020 and 2021 causing death of huge number of
life in the globe. Bangladesh was not an exception. Being a life-threatening disease, it has great impact on the
pharmaceutical companies of any country. The study was aimed to find any difference in performance of some
selected pharmaceutical companies due to Covid-19 pandemic. The medicine and vaccine related with Covid-
19 was in peak of demand that caused to increase the profitability of the companies. However, the normal and
avoidable treatments were deliberately delayed during the period. The study finds no significant difference in
the performance of pharmaceutical companies during the pandemic and after the pandemic.
Keywords: Covid-19 pandemic, Bangladesh, Pharmaceutical companies, profitability performance.
Background of the Study
The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was officially
declared a pandemic by the World Health Organization (WHO) on March 11, 2020. This virus has profoundly
impacted public health systems worldwide, and Bangladesh, as one of the most densely populated countries with
an estimated population of approximately 164 million (World Population Review, 2020), faced significant
challenges in managing the outbreak. The first confirmed COVID-19 cases in Bangladesh were reported on
March 8, 2020, involving returnees from Italy (Hossain, 2020). By September 18, 2020, global COVID-19
infections surpassed 30 million, with over 952,000 fatalities, while Bangladesh recorded more than 345,000
infections and 4,881 deaths (Worldometer, 2020).
The healthcare workforce bore a considerable burden during the pandemic, with significant numbers of
healthcare providers infected; as of August 9, 2020, about 2,531 doctors and 3,011 health workers contracted
the virus, with 73 specialist doctors succumbing to the disease (Hossain, 2020). In this context, the
pharmaceutical industry of Bangladesh plays a crucial role. With approximately 257 licensed manufacturers, the
sector has evolved significantly since the 1980s, establishing Bangladesh as a burgeoning hub for generic drugs
(Faisal, 2019). The industry meets around 98% of local demand for medicines, with about 80% of its output
being generic products (Bangladesh Association of Pharmaceutical Industries [BAPI], 2023).
During the pandemic, Bangladeshi pharmaceutical companies demonstrated their capability by swiftly launching
COVID-19-related products, including Remdesivir, Favipiravir, and Ivermectin. The rapid availability of these
medications garnered international attention, leading to increased exports (Sadek, 2020). The pandemic also
accelerated the adoption of digital marketing and online engagement platforms for pharmaceutical companies,
as traditional marketing practices were disrupted by social distancing measures. Webinars and social media
campaigns became vital tools for maintaining engagement with healthcare professionals and promoting new
products (Islam et al., 2021).
Despite the swift adaptability of the industry, it faces significant challenges due to its reliance on imported raw
materials, particularly Active Pharmaceutical Ingredients (APIs), with approximately 95% sourced from
countries like China and India. The pandemic disrupted global supply chains, threatening the stability of local
medicine production (Mitra et al., 2020). However, through efficient demand management and strategic
INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN SOCIAL SCIENCE (IJRISS)
ISSN No. 2454-6186 | DOI: 10.47772/IJRISS | Volume IX Issue X October 2025
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sourcing, the industry successfully mitigated the potential for a medicine crisis that severely affected other
nations (Sadek, 2020).
The purpose of this study is to analyze and compare the profitability performance of the pharmaceutical industry
in Bangladesh before and after the COVID-19 pandemic. Understanding these dynamics is crucial for
stakeholders in the industry to navigate future challenges and leverage growth opportunities in a post-pandemic
environment.
LITERATURE REVIEW
The COVID-19 pandemic has triggered unprecedented disruptions across various sectors globally, with
significant implications for the pharmaceutical industry. This literature review examines the effects of the
pandemic on the profitability of Bangladesh's pharmaceutical sector, examining historical perspectives, industry
responses, and emerging challenges.
Globally, the COVID-19 pandemic has reshaped the pharmaceutical landscape, forcing companies to adapt
rapidly to maintain operational continuity. Research by Zhang et al. (2021) indicates that supply chain
disruptions, primarily due to restrictions on transportation and trade, severely impacted drug availability and
profitability in numerous countries. The pandemic underscored the importance of local production capabilities
and supply chain resilience, particularly for Active Pharmaceutical Ingredients (APIs), the backbone of
pharmaceutical manufacturing.
Bangladesh's pharmaceutical sector has evolved significantly since the 1980s, becoming a prominent hub for
generic drug production. According to the Bangladesh Association of Pharmaceutical Industries (BAPI),
approximately 257 licensed manufacturers operate within the country, supplying around 98% of local medicine
needs (Faisal, 2019). This historical context is crucial for understanding the industry's readiness to respond to
the challenges posed by the pandemic. The industry's capacity to produce a diverse array of pharmaceuticals,
including generics and specialized products, has positioned it uniquely in the region (Chaudhuri, 2020).
The swift response of Bangladeshi pharmaceutical companies in launching COVID-19-related products, such as
Remdesivir and Ivermectin, highlights the sector's adaptability (Sadek, 2020). The ability to rapidly produce
these essential drugs not only served domestic needs but also attracted international interest, boosting exports to
countries facing shortages. This adaptability is a testament to the industry's technological capabilities and
regulatory framework, enabling quick approval processes for new products (Rahman & Islam, 2022).
The transition from pre-pandemic to pandemic conditions has necessitated a detailed analysis of profitability
metrics within the industry. Initial studies suggest that while some companies experienced growth due to
increased demand for COVID-19 treatments, others faced significant challenges, particularly those reliant on
imports for raw materials (Limbong, 2022). The profitability performance of local manufacturers is linked to
their ability to navigate supply shortages and adapt marketing strategies in response to social distancing
regulations.
Despite its successes, the Bangladeshi pharmaceutical industry confronted significant challenges during the
pandemic. The heavy reliance on imported APIsapproximately 95%complicated the supply chain, leading
to potential threats to production stability (Hossain, 2020). Moreover, the marketing landscape shifted
dramatically, as traditional methods were hampered by lockdowns, prompting companies to pivot to digital
marketing strategies. This shift, while innovative, exposed gaps in digital engagement and regulatory compliance
(Islam et al., 2021).
Looking ahead, the pandemic offers valuable lessons for the pharmaceutical industry in Bangladesh. There is a
pressing need for investment in local API production to reduce dependency on imports, enhancing both resilience
and profitability (Mitra et al., 2020). Additionally, firms are encouraged to continue leveraging digital channels
for marketing and distribution, integrating these strategies into their long-term business models. Future research
should focus on longitudinal studies assessing the lasting impacts of COVID-19 on profitability in the
INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN SOCIAL SCIENCE (IJRISS)
ISSN No. 2454-6186 | DOI: 10.47772/IJRISS | Volume IX Issue X October 2025
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pharmaceutical sector.
This literature review underscores the complex dynamics that have shaped the pharmaceutical industry in
Bangladesh during the COVID-19 pandemic. While the industry demonstrated remarkable resilience and
adaptability, substantial challenges remain, particularly concerning supply chain dependencies. This study aims
to provide a comparative analysis of the profitability performance of the Bangladeshi pharmaceutical sector
before and during the pandemic, contributing to a deeper understanding of the industry's evolution in a crisis
context.
METHODOLOGY OF THE STUDY
Research Design
This study employs an analytical research design, which involves the use of existing facts and data to perform a
critical evaluation. Analytical research is characterized by the application of critical thinking skills to analyze
information and derive new insights or interpretations. It is widely utilized across various fields, including
academia, medicine, and psychology, to develop a deeper understanding of the subject matter and generate
innovative ideas.
Sample and Sampling Method
There are twenty seven pharmaceutical companies listed in Dhaka Stock Exchange and Chittagong Stock
Exchange. Though there are a number of pharmaceutical companies in Bangladesh, a huge number of them are
either not in operation or not doing well. Data of these companies are not available. Even there are some but not
reliable. So we confined our population to these listed companies only.
To select the sample, the simple random sampling method was employed. This approach ensures that each
member of the population has an equal chance of being selected, thereby minimizing bias and providing a
representative subset. However, any deviation from population representation is acknowledged as sampling
error.
The final sample consists of 10 companies (N=10), listed below:
ACI Limited
BEXIMCO Pharmaceuticals Limited
Renata Limited
Wata Chemicals Limited
Square Pharmaceuticals Limited
Orion Pharma Limited
Advent Pharma Limited
BEACON Pharmaceuticals Limited
IBN SINA Pharmaceutical Industry Limited
Orion Infusion Limited
Sources of Data
This study relies exclusively on secondary data sources to collect the necessary information. Secondary data
refers to information that is collected and documented by other individuals or organizations and later utilized for
analysis. The specific sources of secondary data for this study include:
Annual reports of the selected companies
Official company websites
Third-party websites and databases containing information relevant to the selected companies
INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN SOCIAL SCIENCE (IJRISS)
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Study Period
The study compare the financial performance of selected pharmaceutical companies pre-pandemic and post-
pandemic. Financial data of the selected companies for period of 2017, 2018, and 2019 were considered as pre
pandemic. On the other hand data for the period of 2020, 2021 and 2022 were considered for pandemic data.
Hypotheses Development
The hypotheses aim to evaluate the impact of the COVID-19 pandemic on key financial performance
indicatorsReturn on Assets (ROA), Return on Equity (ROE), and Profit Marginof the pharmaceutical
industry. The null (H0) and alternative (HA) hypotheses are as follows:
1. Effect on Return on Assets (ROA):
H0: There is no significant difference in ROA between the pre-COVID-19 and post-COVID-19
periods for the pharmaceutical industry.
HA: There is a significant difference in ROA between the pre-COVID-19 and post-COVID-19
periods for the pharmaceutical industry.
2. Effect on Return on Equity (ROE):
H0: There is no significant difference in ROE between the pre-COVID-19 and post-COVID-19
periods for the pharmaceutical industry.
HA: There is a significant difference in ROE between the pre-COVID-19 and post-COVID-19
periods for the pharmaceutical industry.
3. Effect on Profit Margin:
H0: There is no significant difference in profit margins between the pre-COVID-19 and post-
COVID-19 periods for the pharmaceutical industry.
HA: There is a significant difference in profit margins between the pre-COVID-19 and post-COVID-
19 periods for the pharmaceutical industry.
Statistical Methods Used
The hypothesis developed were tested using the paired sample t-test. As the paired sample t-test (also known
as the dependent t-test) is used when two sets of observations are related or come from the same subjects
measured at two different times, this test was used in this study (Cressie & Whitford 1986).
Comparison of Return on Asset (ROA) of Pre and Post COVID-19 Situation;
Data of Return on Asset (ROA) of Pre and During COVID-19 Situation are stated below;
Particulars
Pre COVID-19 (%)
Post COVID-19 (%)
ACI Limited
2.63
-0.62
BEXIMCO Pharma Ltd
6.99
8.41
Renata Limited
17.57
14.10
Wata Chemicals Ltd
3.92
4.14
SQUARE Pharma Ltd
19.37
16.51
Orion Pharma Ltd
2.88
2.01
Advent Pharma Limited
12.65
8.00
BEACON Pharma Ltd
2.06
7.71
IBN SINA Pharma Ind. Ltd
13.25
12.07
Orion Infusion Ltd
7.55
4.19
Source: Author’s calculation based on annual report.
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Paired Samples Statistics
N
Std. Deviation
Std. Error Mean
Pair 1
Pre COVID-19
10
6.41
2.02
Post COVID-19
10
5.42
1.71
The above table indicates that the Return on Asset (ROA), Mean (M) of Pre COVID-19 is 8.88 with a standard
deviation of 6.41. Again, the Return on Asset (ROA), Mean (M) of During COVID-19 is 7.65 with a standard
deviation of 5.42.
Paired Samples t-test
Paired Differences
t
df
Sig. (2-
tailed)
Mean
Std.
Deviation
Std.
Error
Mean
95% Confidence Interval of
the Difference
Lower
Upper
Pair
1
Pre COVID-19
- Post COVID-
19
1.23
3.06
.97
-.95
3.42
1.27
9
0.23
The above table includes the result of Paired T-Test. The Mean (M) is 1.23 with a Standard Deviation of 3.06.
It also contain the value of T i.e. 1.27 and value of P i.e. 0.23
Decision: As P value in 0.23 i.e. above 5.00 % or 0.05, the null Hypothesis is accepted. Therefore, there is no
difference in the return on asset (ROA) between Pre and post COVID-19 situation of Pharmaceutical industry.
Comparison of Return on Equity (ROE) of Pre and post COVID-19:
Particulars
Pre COVID-19
Post COVID-19
ACI Limited
9.52
-5.01
BEXIMCO Pharma Ltd
10.32
12.33
Renata Limited
25.65
19.06
Wata Chemicals Ltd
8.76
11.91
SQUARE Pharma Ltd
20.81
17.40
Orion Pharma Ltd
4.82
4.37
Advent Pharma Limited
22.67
9.82
BEACON Pharma Ltd
3.42
12.17
IBN SINA Pharma Ind. Ltd
26.02
22.44
Orion Infusion Ltd
20.29
10.99
Source: Author’s calculation
Paired Samples Statistics
Mean
N
Std. Deviation
Std. Error Mean
Pair 1
Pre COVID-19
15.22
10
8.71
2.75
Post COVID-19
11.54
10
7.74
2.44
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The above table indicates that the Return on Equity (ROE), Mean (M) of Pre COVID-19 is 15.22 with a standard
deviation of 8.71. Again, the Return on Equity (ROE), Mean (M) of During COVID-19 is 11.54 with a standard
deviation of 7.74.
Paired Samples Test
Paired Differences
t
df
Sig. (2-
tailed)
Mean
Std.
Deviation
Std.
Error
Mean
95% Confidence Interval
of the Difference
Lower
Upper
Pair 1
Pre COVID-19
- post COVID-
19
3.68
7.34
2.32
-1.57
8.93
1.58
9
0.14
The above table includes the result of Paired T-Test. The Mean (M) is 3.68 with a Standard Deviation of 7.34.
It also contain the value of T i.e. 1.58 and value of P i.e. 0.14
Decision: As P value in 0.14 i.e. above 5.00 % or 0.05, the null Hypothesis is accepted. Therefore, there is no
difference in the return on Equity (ROE) between Pre and post COVID-19 situation of Pharmaceutical industry.
Comparative Analysis of Profit Margin of Pre and Post COVID-19:
Particulars
Pre COVID-19 (%)
Post COVID-19 (%)
ACI Limited
2.05
-0.55
BEXIMCO Pharma Ltd
14.17
15.55
Renata Limited
20.36
16.57
Wata Chemicals Ltd
11.59
15.73
SQUARE Pharma Ltd
26.78
30.28
Orion Pharma Ltd
9.48
8.69
Advent Pharma Limited
18.96
22.43
BEACON Pharma Ltd
2.97
9.47
IBN SINA Pharma Ind. Ltd
6.94
6.49
Orion Infusion Ltd
7.14
3.92
Source: Author’s calculation
Paired Samples Statistics
Mean
N
Std. Deviation
Std. Error Mean
Pair 1
Pre COVID-19
12.04
10
8.01
2.53
Post COVID-19
12.85
10
9.15
2.89
The above table indicates that the Profit Margin, Mean (M) of Pre COVID-19 is 12.04 with a standard deviation
of 8.01. Again, the Profit Margin, Mean (M) of post COVID-19 is 12.85 with a standard deviation of 9.15.
INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN SOCIAL SCIENCE (IJRISS)
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Paired Samples Test
Paired Differences
t
df
Sig. (2-
tailed)
Mean
Std.
Deviation
Std.
Error
Mean
95% Confidence Interval
of the Difference
Lower
Upper
Pair
1
Pre COVID-19 -
post COVID-19
-0.81
3.51
1.11
-3.32
1.70
-0.72
9
0.48
The above table includes the result of Paired T-Test. The Mean (M) is -0.81 with a Standard Deviation of 3.51.
It also contain the value of T i.e. -0.72 and value of P i.e. 0.48
Decision: As P value in 0.48 i.e. above 5.00 % or 0.05, the null Hypothesis is accepted. Therefore, there is no
difference in the return on Equity (ROE) between Pre and post COVID-19 situation of Pharmaceutical industry.
CONCLUSION AND IMPLICATION
This is first time Bangladesh economy is facing a global pandemic after the independence. It’s obvious that the
individual, firms and organization are experiencing a different scenario and enforced to execute different
restriction in public interaction and trade & commerce. The restriction forced to bring a change in the day to day
life and trade & commerce within different sector of the economy. Bangladesh economy was badly affected by
the COVID-19. Almost every industry faced a financial crisis during this situation and Pharmaceutical Industry
is one of them. The country was facing a global pandemic for first time, healthcare & pharmaceutical sector was
initially in lack of availability of raw materials and expertize to face the evolving challenges. But, later on those
industries worked hard to overcome the shortage and fulfill the national demand of the healthcare products.
Taking an advantage of this situation, many companies with unethical behavior involved themselves in price
hiking of medicine and other healthcare products and corruption regarding vaccine and COVID reports etc. This
scenario forced to build an assumption that the pharmaceutical industry was boosted during the pandemic
situation. But, the above study includes paired sample T-Test which revealed that there is no difference in the
profitability performance between Pre and post COVID-19 situation of Pharmaceutical industry of Bangladesh.
It also exhibits the growth of Total asset, Total equity & Revenue of the sample companies within the
pharmaceutical industry of Bangladesh.
REFERENCES
1. Bangladesh Association of Pharmaceutical Industries. (2023). Annual report on pharmaceutical
production in Bangladesh. Dhaka: Author. http://www.bapi-bd.com/bangladesh-pharma-
industry/overview.html
2. Cressie, N. A. C., & Whitford, H. J. (1986). How to use the two sample t‐test. Biometrical Journal,
28(2), 131-148.
3. Chaudhuri, S. (2020). Evolution of the pharmaceutical industry Bangladesh, 1982 to 2020. Centre for
Development Studies, Working Paper, 495.
4. Faisal. A. (2019). Pharmaceuticals Industry of Bangladesh (3rd Edition), CFA Institute Asia-Pacific
Research Exchange (ARX)
https://www.arx.cfa/~/media/2A85F9B2CEAB43CFAF325AB54F3EF404.ashx
5. Hossain J. (2020), Impact of COVID-19 Pandemic among Health Care Providers in Bangladesh: A
Systematic Review, Bangladesh Journal of Infectious Diseases 7(2),
https://doi.org/10.3329/bjid.v7i00.50156
6. Limbong, G. (2022). Analysis of the company's financial performance before and during the Covid-
19 pandemic (2019-2020) in pharmaceutical sector companies listed on the IDX. Jurnal
Manajemen, 10(2), 156-165.
INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN SOCIAL SCIENCE (IJRISS)
ISSN No. 2454-6186 | DOI: 10.47772/IJRISS | Volume IX Issue X October 2025
Page 9383
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7. Sadek, A.Z. (2020). Pharmaceutical business in Bangladesh during Covid-19 pandemic, The Business
Standard, https://www.tbsnews.net/thoughts/pharmaceutical-business-bangladesh-during-covid-19-
pandemic-144481
8. World meter. (2020, September 18). COVID-19 Coronavirus pandemic data. Retrieved from
https://www.worldometers.info/coronavirus/
9. Zhang, A., Wang, J. X., Farooque, M., Wang, Y., & Choi, T. M. (2021). Multi-dimensional circular
supply chain management: A comparative review of the state-of-the-art practices and
research. Transportation Research Part E: Logistics and Transportation Review, 155, 102509.