INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN SOCIAL SCIENCE (IJRISS)  
ISSN No. 2454-6186 | DOI: 10.47772/IJRISS | Volume IX Issue X October 2025  
Needlestick and Sharps Injuries among Nurses: A Systematic Review  
of Occupational Safety and Health Practices  
Joemmaicca Augustta Joggery., Kamariah Hussein., Siti Fatimah Md. Shariff., Rozila Ibrahim.,  
Zuraida Jorkasi., Aniszahura Abu Salim., Noor Siah Abd Aziz., Zaimatul Ruhaizah Kamarazaman  
Faculty of Technology and Applied Sciences, Open University Malaysia  
Received: 02 November 2025; Accepted: 10 November 2025; Published: 24 November 2025  
ABSTRACT  
Needlestick and sharps injuries (NSIs) remain one of the most significant occupational hazards among nurses,  
exposing them to blood-borne pathogens and psychological distress. This systematic review synthesised  
evidence from 15 empirical and review papers published between 2012 and 2025, focusing on the prevalence,  
associated factors, knowledge, attitudes, practices (KAP), and occupational safety and health (OSH) measures  
associated with NSIs among nurses and closely related healthcare groups. A PRISMA-informed process was  
applied to a comprehensive search across Google Scholar, PubMed, and MEDLINE, which initially identified  
1,265 records; following screening and eligibility assessment, 15 studies met inclusion criteria. The included  
studies, conducted across Asia, the Middle East, and Europe, consistently showed that NSIs are highly prevalent,  
frequently under-reported, and closely linked to gaps in training, inconsistent adherence to standard precautions,  
and system-level challenges such as weak reporting systems and limited follow-up of exposed workers.  
Knowledge and awareness of NSI prevention were generally moderate, yet gaps persisted in actual practice,  
including safe injection behaviours, sharps disposal, incident reporting, and post-exposure management. Only a  
minority of studies examined structured OSH prevention strategies comprehensively. Overall, the findings  
highlight the urgent need for multifaceted OSH programs integrating safety-engineered devices, continuous  
education, strengthened reporting mechanisms, and institutional support to effectively protect nurses.  
Needlestick injuries, Sharps injuries, Nurses, Occupational safety, Safety practices  
INTRODUCTION  
Needlestick and sharps injuries (NSIs) represent one of the most serious occupational hazards faced by nurses  
due to their frequent involvement in invasive procedures and handling of sharp medical devices. NSIs can expose  
nurses to blood-borne pathogens such as hepatitis B, hepatitis C, and HIV, with profound physical,  
psychological, and occupational consequences. Numerous studies from varied healthcare settings consistently  
report NSIs as a continuing challenge for nursing personnel (Abdul Wahab et al., 2019; Ehsani et al., 2012; Ishak  
et al., 2019; Kim & Lee, 2015).  
Beyond direct clinical risks, NSIs reflect deeper occupational safety and health (OSH) system issues, including  
inadequate training, inconsistent adherence to standard precautions, staffing shortages, high workload,  
insufficient access to safety devices, and weak post-exposure management protocols (Alabdli et al., 2024; Ghanei  
Gheshlagh et al., 2025). Under-reporting of NSIs remains a critical barrier to accurate surveillance and  
institutional improvement. For instance, Voide et al. (2012) demonstrated widespread under-reporting in a Swiss  
university hospital, reducing the effectiveness of OSH initiatives.  
While knowledge, attitudes, and practices (KAP) are central to NSI prevention, evidence suggests that awareness  
does not always translate into safe behaviours. Studies involving nurses and nursing students indicate persistent  
gaps in sharps handling, disposal, and follow-up adherence (Azman et al., 2022; Xin, 2020; Yazid et al., 2023).  
Even when NSIs are reported, follow-up procedures and PEP completion are often inconsistent (Mohd Fadhli et  
al., 2018; Mohamud et al., 2023).  
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Recent work has emphasized the need for OSH-focused interventions, highlighting the value of integrating  
engineering controls, administrative policies, and sustained education into safety programmes (Alabdli et al.,  
2024). Other studies have contributed epidemiological data, identifying patterns and determinants of NSIs across  
various healthcare settings (Ehsani et al., 2012; Ishak et al., 2019; Kim & Lee, 2015; Mohamud et al., 2023;  
Mohammed & Mahmood, 2025; Ghanei Gheshlagh et al., 2025).  
Given the continued burden of NSIs and increasing interest in OSH-prevention frameworks, a targeted synthesis  
of evidence is warranted to support improved safety protocols for nurses.  
Objectives  
1. To summarise the prevalence and epidemiological patterns of needlestick and sharps injuries among  
nurses.  
2. To examine individual and organisational factors associated with NSIs, including knowledge, attitudes,  
practices (KAP), and workplace conditions.  
3. To identify OSH-related practices and interventions for NSI prevention and post-exposure management.  
4. To highlight gaps in current evidence and propose implications for policy, practice, and future research.  
Design And Reporting  
This study is a systematic literature review conducted according to the Preferred Reporting Items for Systematic  
Reviews and Meta-Analyses (PRISMA) 2020 guidelines. The review adhered to the four PRISMA stages:  
identification, screening, eligibility, and inclusion. A comprehensive search was performed in Google Scholar,  
PubMed, and MEDLINE, yielding 1,265 records.  
Eligibility Criteria  
Studies were included if they met the following criteria:  
i. Population: Nurses; studies involving other healthcare workers or students were eligible if NSI-related  
outcomes were applicable to nursing practice.  
ii. Exposure/Outcome: Needlestick or sharps injuries; prevalence, incidence, risk factors, KAP, reporting,  
follow-up, or OSH practices linked to NSIs.  
iii. Study Design: Quantitative observational studies (cross-sectional, retrospective, meta-analysis) or narrative  
reviews.  
iv. Setting: Hospital, clinical, or educational healthcare environments  
v. Language: English; peer-reviewed articles only.  
Information Sources  
A comprehensive search of Google Scholar, PubMed, and MEDLINE identified 1,265 records. Database  
searches were supplemented by citation tracking. After removing 312 duplicates, 953 records proceeded to  
title/abstract screening. No additional searches were conducted outside these databases.  
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Figure 1: Prisma Guideline 2020  
Data Extraction and Items  
Data extraction for this review was conducted systematically, guided by the PRISMA 2020 recommendations to  
ensure accuracy, uniformity, and transparency. A structured data extraction matrix was developed to capture all  
relevant information from each included study. For every article, the reviewers recorded the author and year of  
publication to establish the temporal distribution of research and identify any shifts in NSI trends over time. The  
country and healthcare setting were documented to contextualise findings geographically and organisationally,  
recognising that NSI prevalence and prevention practices vary widely across regions and health systems.  
The study design was extracted to classify whether the article used cross-sectional, retrospective, review, or  
meta-analytic methods, as differences in design influence the strength and interpretability of findings.  
Information regarding the sample size and population characteristics was also recorded, including whether the  
participants were nurses, other healthcare workers, students, or dental personnel. This helped determine the  
representativeness and relevance of each study to nursing practice.  
Key NSI-related outcomes such as prevalence, incidence, recurrence, and patterns of exposure were  
systematically documented. The reviewers also extracted reported risk and associated factors, ranging from  
individual-level determinants such as experience, fatigue, and adherence to standard precautions, to system-level  
conditions including workload, staffing adequacy, and availability of safety devices. In studies examining  
behavioural aspects, the reviewers summarised the knowledge, attitudes, and practices (KAP) of participants  
regarding NSI prevention, sharps handling, disposal, and post-exposure responses.  
Given the importance of institutional responses to NSIs, particular attention was paid to reporting behaviours  
and follow-up adherence, including whether affected nurses completed serological testing, post-exposure  
prophylaxis (PEP), or subsequent clinical monitoring. Finally, any occupational safety and health (OSH)  
interventions or recommendations such as training programs, safety-engineered devices, policy improvements,  
or administrative controls were extracted to support the synthesis of prevention strategies.  
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Synthesis of Results  
Due to substantial methodological heterogeneity across the included studies particularly differences in study  
design, population characteristics, measurement tools, and types of outcomes assessed, a quantitative meta-  
analysis was not appropriate. Instead, the review employed a narrative thematic synthesis, which allowed for the  
integration of diverse forms of evidence while maintaining conceptual coherence.  
The synthesis process involved repeated reading, coding, and categorisation of extracted data, followed by  
clustering of similar findings into broader conceptual themes. Four major themes were developed through this  
iterative process. The first theme, Epidemiology, encompassed trends in prevalence, types of injuries, and  
patterns of exposure across clinical departments and countries. The second theme, Risk Factors, captured both  
individual-level determinants such as experience, behaviour, or fatigue and organisational influences such as  
workload, availability of sharps containers, and OSH system strength. The third theme, Knowledge, Attitudes,  
Practices, and Reporting, examined behavioural competence, perceived barriers, reporting culture, and  
adherence to follow-up procedures. The fourth theme, OSH Prevention Practices, synthesised recommendations  
and interventions at institutional and system levels, including engineering controls, training initiatives, and  
policy frameworks.  
Quality Assessment and Risk of Bias  
Although a formal risk-of-bias tool such as the Joanna Briggs Institute (JBI) checklist or the Newcastle-Ottawa  
Scale was not systematically applied, the review incorporated a descriptive assessment of methodological quality  
to support critical interpretation of findings. The evaluation focused on several key indicators, including the  
appropriateness of sampling methods, representativeness of the sample, and the clarity of outcome definitions  
for NSIs. Studies that clearly described inclusion criteria, operational definitions, and data collection processes  
were considered more methodologically robust.  
Response rates and completeness of reporting were also noted, as studies with low response rates or incomplete  
data may be more susceptible to bias. In addition, reviewers assessed whether the studies acknowledged and  
addressed limitations, which enhances transparency and helps contextualise findings.  
Common risks of bias identified across the included studies included recall bias, particularly in self-reported  
surveys where participants were asked to remember past NSI events. Under-reporting was another major  
concern, as several studies relied on voluntary reporting systems known to underestimate true NSI incidence.  
Furthermore, heavy reliance on self-report measures posed risks of social desirability bias and misclassification.  
These methodological considerations were incorporated into the interpretation of results, ensuring that  
conclusions were grounded in a balanced appraisal of the strengths and limitations of the underlying evidence.  
RESULTS  
Characteristics of Included Studies  
A total of 15 studies were included in this review, representing diverse geographical regions including Malaysia,  
Iran, Pakistan, South Korea, Somalia, Iraq, Switzerland, and Saudi Arabia. Most of the studies adopted a cross-  
sectional design, while two were reviews and one was a meta-analysis. Sample sizes varied considerably across  
studies, ranging from fewer than 100 participants to more than 1,000 healthcare workers, although nurses  
consistently formed the primary population of interest. Several studies also involved mixed groups such as  
medical students, dental personnel, or other allied health workers, but were included when the outcomes were  
directly relevant to nursing practice or sharps-handling safety. Across the body of evidence, the studies measured  
key outcomes including the prevalence of needlestick and sharps injuries, associated individual and  
organisational risk factors, knowledge and awareness levels, attitudes and practices, reporting behaviour, and  
adherence to post-exposure follow-up procedures. Although methodological quality varied, most studies clearly  
described their data collection processes and provided statistically analysable findings suitable for synthesis.  
However, reliance on self-reported survey data was common, suggesting an inherent risk of recall and social  
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desirability bias.  
Author  
Country  
Study Design Population  
Sample Key Outcomes  
Size  
Abdul Wahab et al. Malaysia  
(2019)  
Cross-sectional Healthcare workers 170  
(including nurses)  
NSI  
prevalence,  
follow-up adherence  
Akyol & Kargın Turkey  
(2016)  
Cross-sectional Nurses  
109  
NSI patterns, risk  
behaviours  
Alabdli et al. (2024) Multi-  
country  
Review  
Nurses  
NSI prevention and  
OSH strategies  
Almoliky et al. Saudi  
Cross-sectional Nurses  
538  
NSI prevalence and  
associated factors  
(2024)  
Arabia  
Azman et al. (2022) Malaysia  
Cross-sectional Medical, nursing & 350  
paramedic students  
Knowledge  
awareness of NSIs  
and  
Ehsani et al. (2012) Iran  
Cross-sectional Nurses  
200  
Epidemiology  
NSIs  
of  
Ghanei Gheshlagh Pakistan  
et al. (2025)  
Meta-analysis  
Nurses  
students  
&
nursing 1,000+  
Pooled prevalence of  
NSIs  
Ishak et al. (2019)  
Malaysia  
Cross-sectional Healthcare workers  
1,002  
287  
457  
203  
370  
210  
661  
250  
Prevalence  
reporting  
&
Kim & Lee (2015) South Korea Cross-sectional Nurses  
Risk factors & injury  
patterns  
Mohamud et al. Somalia  
(2023)  
Retrospective  
review  
Healthcare workers  
NSI  
trends  
&
reporting  
Mohd Fadhli et al. Malaysia  
(2018)  
Cross-sectional Healthcare workers  
Cross-sectional Nurses  
Follow-up protocol  
adherence  
Mohammed  
& Iraq  
NSI prevalence  
determinants  
&
Mahmood (2025)  
Voide et al. (2012) Switzerland Observational Healthcare workers  
Under-reporting  
NSIs  
of  
Xin (2020)  
China  
Cross-sectional Dental personnel  
Cross-sectional Nurses  
Knowledge & safety  
practices  
Yazid et al. (2023) Malaysia  
Prevalence and Epidemiology of NSIs  
KAP related to NSIs  
The prevalence of needlestick and sharps injuries across the included studies was consistently high, with reported  
rates ranging widely from approximately 19% to more than 70% among nurses and related healthcare personnel.  
Several studies documented multiple NSI events among individual healthcare workers, indicating recurrent  
exposure risks in busy clinical environments. The majority of injuries were caused by hollow-bore needles,  
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followed by suture needles and lancets, particularly in departments with high patient turnover such as emergency  
units, medical wards, intensive care units, and phlebotomy services. Under-reporting of NSIs was a recurrent  
issue across the studies, especially in settings with less structured occupational safety systems; this phenomenon  
was strongly highlighted in the Swiss study by Voide et al. (2012), which reported significantly lower  
documented cases than estimated actual occurrences. Meta-analytic findings from Pakistan further reinforced  
the high burden of NSIs, suggesting that younger nurses and those with fewer years of experience face  
disproportionately higher risks. Collectively, the evidence demonstrates that NSIs remain a persistent and  
significant occupational hazard across diverse healthcare systems.  
Risk Factors Associated with NSIs  
Both individual and organisational factors contributed to NSI occurrence. Individual-level risks included limited  
clinical experience, inadequate training on safe sharps-handling practices, fatigue, extended working hours, shift  
rotation, and non-adherence to standard precautions. Unsafe behaviours such as needle recapping, improper  
disposal of sharps, hurried clinical procedures, and failure to use personal protective equipment (PPE) were  
widely reported. Organisational factors were equally prominent, with multiple studies citing heavy workloads,  
staff shortages, overcrowded clinical areas, lack of functional sharps containers, and inadequate availability of  
safety-engineered devices. Weak occupational safety and health infrastructures, absence of regular training  
updates, and inconsistent supervision further exacerbated NSI risks. Notably, several studies highlighted that  
even when nurses possessed adequate knowledge, systemic pressures such as time constraints or workload  
demand hindered their ability to practise safely.  
Knowledge, Attitudes, Practices (KAP) and Reporting Behaviour  
Findings on knowledge, attitudes, and practices were mixed. Knowledge of NSI risks and prevention measures  
was generally moderate to high among nurses and students; however, this knowledge did not consistently  
translate into safe clinical behaviours. Attitudinal barriers such as fear of blame, reluctance to report incidents,  
and perceptions that an injury was "minor" contributed to the widespread under-reporting of NSIs. Many nurses  
reported that incident reporting procedures were time-consuming or not well supported by supervisors, which  
discouraged appropriate follow-up. Studies also showed that post-exposure management practices were often  
incomplete; although some nurses-initiated reporting, many did not complete the recommended serology testing  
or post-exposure prophylaxis (PEP), largely due to workflow constraints or lack of institutional support. Overall,  
KAP findings suggest a disconnect between theoretical understanding and actual behaviour, underscoring the  
need for stronger safety culture development.  
Occupational Safety and Health (OSH) Prevention Practices  
The review found that relatively few studies evaluated OSH interventions in depth. Among those that did,  
commonly reported measures included structured training programmes, continuous professional development  
sessions, safety audits, and implementation of safety-engineered devices such as retractable needles. Where  
safety-engineered devices were available and properly used, injury rates were significantly reduced.  
Administrative controls such as clear reporting protocols, supportive supervisory structures, and mandatory  
follow-up pathways were also shown to improve safety outcomes. However, implementation of OSH measures  
varied widely between countries and healthcare institutions, with resource-limited settings demonstrating lower  
uptake of engineering controls and weaker reporting systems. These disparities highlight the need for harmonised  
OSH strategies and stronger policy enforcement across healthcare facilities.  
DISCUSSION  
This review synthesised current evidence on needlestick and sharps injuries among nurses and related healthcare  
groups, revealing that NSIs continue to pose a major occupational hazard despite long-standing global efforts to  
reduce such injuries. High prevalence rates across diverse settings demonstrate that NSIs remain a systemic  
challenge rather than an isolated clinical issue. Individual behavioural factors contribute significantly to NSI  
risk; however, many of these behaviours are reflections of deeper structural and organisational shortcomings  
such as heavy workloads, insufficient staffing, limited resources, and lack of access to safety-engineered devices.  
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Knowledge gaps alone do not appear to fully explain unsafe practices, as several studies reported that nurses  
with moderate to high levels of knowledge continued to engage in high-risk behaviours. This reinforces the  
argument that institutional culture, behavioural reinforcement, and supportive supervision are critical factors in  
ensuring adherence to safety practices. Furthermore, widespread under-reporting of NSIs remains a significant  
obstacle to effective surveillance, prevention, and policymaking. Under-reporting delays initiation of PEP and  
obstructs accurate identification of high-risk areas, thereby weakening organisational safety systems.  
Collectively, the findings emphasise the importance of integrating engineering controls, administrative policies,  
educational interventions, and safety culture development into a comprehensive OSH framework.  
Limitations Of The Review  
This review is subject to several limitations. First, only English-language articles were included, which may have  
resulted in the omission of relevant evidence published in other languages. Second, the search was limited to  
Google Scholar, PubMed, and MEDLINE; inclusion of additional databases may have yielded a broader sample  
of studies. Third, many of the included studies relied on self-reported data, making them susceptible to recall  
and social desirability bias. Fourth, although methodological limitations of each study were acknowledged, a  
formal risk-of-bias appraisal tool was not applied, which may affect the depth of critical assessment. Lastly,  
heterogeneity in study designs, populations, and outcome measures precluded meta-analysis, limiting the review  
to narrative synthesis.  
RECOMMENDATIONS  
The findings of this review suggest several important implications for practice, policy, and research. For nursing  
practice, continuous training programmes and competency-based assessments should be implemented to  
strengthen safe sharps-handling behaviours. Institutions must ensure adequate supply of safety-engineered  
devices, enforce strict adherence to standard precautions, and support timely disposal of sharps.  
From a policy perspective, healthcare facilities should implement mandatory NSI reporting systems, establish  
structured post-exposure prophylaxis pathways, and conduct regular workplace safety audits. National OSH  
frameworks should emphasise engineering controls, supportive supervision, and a non-punitive reporting  
culture.  
Future research should adopt standardised definitions and measurement tools for NSIs to enable comparability  
across studies. Prospective, multi-centre studies are needed to reduce reliance on self-reporting and strengthen  
the evidence base. Additionally, more research should be conducted on behavioural and organisational  
interventions designed to improve reporting behaviour and follow-up compliance.  
CONCLUSIONS  
This systematic review demonstrates that needlestick and sharps injuries remain a substantial occupational  
hazard among nurses, with persistent high prevalence rates, recurrent injuries, and significant gaps in reporting  
and follow-up behaviours. Despite moderate knowledge levels, unsafe practices continue to occur due to a  
combination of individual behaviour and systemic institutional factors. Strengthening OSH systems through  
continuous education, safety-engineered devices, structured reporting pathways, and supportive workplace  
cultures is essential to reducing NSI incidence and protecting nurses’ health and well-being.  
ACKNOWLEDGMENT  
The authors would like to extend their sincere appreciation to Open University Malaysia (OUM) for the  
continuous academic support and guidance provided throughout the completion of this systematic review. The  
authors are also grateful to the faculty members and colleagues who contributed their expertise, constructive  
feedback, and encouragement during the development of this manuscript. Special thanks are extended to the  
librarians and research support teams who assisted in accessing relevant databases, as well as to all researchers  
whose work formed the foundation of this review. Their collective contributions have significantly enhanced  
the quality and depth of this study.  
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