Dengue without Warning Sign Associated with Unilateral Maculopathy :AnUnusual case

As we all know dengue is viral infection caused by RNA virus of genus flavivirus which is transmitted by Aedes aegypti mosquito. Dengue maculopathy is a rare cause of visual morbidity. We have a 30 years old male presented with gradual painless diminution of vision in his left eye for 20 days. At the time of presentation his vision was hand movement close to face. He was diagnosed case of dengue fever for which he was treated outside one month back. Fundoscopy of left eye shows multiple yellowish deposits at the fovea. Optical coherence tomography and optical coherence tomography angiography was done to rule out Dengue maculopathy. The diagnosis is unusual and most cases will recover without treatment however to prevent from permanent visual damage frequent follow ups would be recommended.

Dengue, flavivirus, foveolitis, maculopathy, optical coherence tomography angiography

1. Kuhn, R.J, Zhang, W et al. Structure of Dengue Virus: Implications for Flavivirus Organization, Maturation, and Fusion. Cell. 2002;108(5):717-25.[DOI] [Google Scholar] [Crossref]

2. Su DHW, Bascal K, et al. Prevalence of dengue maculopathy in patients hospitalized for dengue fever. Ophthalmol. 2007; 114(9): 1743-7.[PMID] [Google Scholar] [Crossref]

3. Teoh, S.C.B, Chana, D.P.L et al. A Re-Look at Ocular Complications in Dengue Fever and Dengue Haemorrhagic Fever. Dengue Bulletin.2006; 30: 183-193. [Google Scholar] [Crossref]

4. Lim WK, Mathur R et al. Ocular manifestations of dengue fever. Ophthalmolol. 2004 ;11(11): 2057–64.[PMID] [Google Scholar] [Crossref]

5. Gubler DJ: The changing epidemiology of yellow fever and dengue, 1900 to 2003: full circle? Comp Immunol Microbiol Infect Dis. 2004;27(5):319–30.[PMID] [Google Scholar] [Crossref]

6. Bascal KE et al. Dengue-associated maculopathy. Arch Ophthalmol. 2007; 125(4): 501-10.[PMID] [Google Scholar] [Crossref]

7. Loh BK et al. Foveolitis associated with dengue fever: A case series. Ophthalmologica. 2008; 222(5): 317-320. [PMID] [Google Scholar] [Crossref]

• Measuring Waste of Patient Time in Health Care at Non-Digitized Hospital: An Observational Study in Bangabandhu Sheikh Mujib Medical University, Bangladesh
• Reaffirming Clinical Confidence in Atorvastatin Therapy: A Digital Outreach Case Study from Tamil Nadu, India
• Clinical Manifestations and Therapeutic Response in a Patient with Hypothyroidism: A Case Report
• Eranda (Ricinus Communis) In Gridhrasi (Sciatica): Classical Rationale, Pharmacology and Clinical Evidence- A Narrative Literature Review
• Magnetotherapy in Pain Management: Mechanisms, Clinical Applications, and Future Perspectives – A Review