A suggestive evaluation and review on the synergy of Renin Angiotensin Aldosterone System (RAAS) and Immune response towards Covid-19
- August 27, 2021
- Posted by: rsispostadmin
- Categories: Biochemistry, IJRIAS
International Journal of Research and Innovation in Applied Science (IJRIAS) | Volume VI, Issue VII, July 2021|ISSN 2454-6194
*Abba Mohammed1 M.I. Shago1, G. Suleiman2 and M.U. Nasir2
1 Department of Biochemistry, Yobe State University, Damaturu, Nigeria
2 Department of Chemistry, Yobe State University, Damaturu, Nigeria
Abstract:- Globally, a “pause mode” to several activities has choicelessly been opted “on” to some extent as Covid-19 has bedeviled the life of humanity since December 2019. As a result, economical, educational, sociological and lots of fundamental paradigms were all inaccessible. Angiotensin Converting Enzyme 2 (ACE 2) paving a way to the incorporation of the SARS-CoV-2 by receptor mediation into the cells has to be scientifically focused towards an inoculative approach to synergically scotch the aiding capacity as well, within all the complications. The inoculation is dared to further boost the immunological responses towards the immunopathological fight against the slipped virus if at all the CoV-2 adversely escaped to adapt on the receptors of the ACE 2. However, all these is as a result so far that the natural innate and the adaptive immune systems are finding it quite tough to hastily invade the pathogens and defend the human body system against the Covid-19 in some patients. Meanwhile, ingesting food of high great value of supplements in upshooting immune system as well as ensuring physical fitness and environmental hygiene are paramount to adherence in this trying moments and indeed all the time, as the world is looking forward to unveiling the veritable vaccine and outright therapeutics against the Corona virus.
Key words:- Severe Acute Respiratory Syndrome-Corona Virus-2, Angiotensin Converting Enzyme 2, Immunopathological.
I. INTRODUCTION
The world is traumatizing and humans are dying. According to World Health Organization (WHO), as of 16th August 2020, more than 21.5 million people have been affected with coronavirus and about 771,000 people have died worldwide. The world experienced coronavirus for the first time in 2002–2003 by Severe Acute Respiratory Syndrome (SARS) and in 2011 by Middle East Respiratory Syndrome (MERS). The causative agents for both cases (SARS-CoV and MERS-CoV, respectively) were newly identified coronavirus with zoonotic origin in the genus Beta coronavirus (Eakachai et al., 2020). The present corona virus (SARS-CoV-2) COVID-19 appeared for the first time in Wuhan, China, at the end of 2019. People are being affected by human to human transmission due to close contact (Yan-Rong et al., 2020; Guan et al., 2020). People affected by COVID-19 suffer from severe respiratory illness (Guan et al., 2020). People who are elderly and have numerous comorbidities are the most vulnerable to this virus (Kwok et al., 2020).
