International Journal of Research and Scientific Innovation (IJRSI) |Volume IX, Issue XI, November 2022|ISSN 2321-2705
Ardi Mohamad Bukhari, Supriyana, Lanny Sunarjo, Suharyo Hadisaputro, Endah Aryati Ekoningtyas
Posgraduate Program of Dental and Oral Therapist, Semarang Health Polytechnic, Indonesia
Abstract: Chronic periodontitis is a multifactorial infectious disease of the dental support tissue caused by microorganisms. Porphyromonas gingivalis is a bacterium that has an important role in the initiation, growth, and severity of chronic periodontitis. So far, periodontitis treatment is carried out with scaling therapy or using chemical topical antibacterial agents such as aloclair gel. This topical antibacterial ingredient has side effects. For this reason, it is necessary to conduct research to prove herbal ingredients as a potential to inhibit the bacteria Porphyromonas gingivalis, the cause of periodontitis which is expected to contribute to dental therapy services. The purpose of this study was to prove robusta coffee bean gel alkaloid and flavonoids compounds of various concentrations in inhibiting the growth of porphyromonas gingivalis.The study used True Experiment post test only control group design. The subjects used the bacteria porphyromonas gingivalis ATCC 33277 with Suspense Mc Farland 0.5. Inhibitory power test using disc diffusion method. The Results of Robusta coffee bean gel alkaloid compounds all concentrations of 0.39%, 0.78%, 1.56% have inhibitory power with a weak category (<5mm) and are less effective in inhibiting the growth of porphyromonas gingivalis bacteria and robusta coffee bean gel flavonoid compounds concentrations of 0.39% and 0.78% have inhibitory power with a weak category (<5 mm), while a concentration of 1.56% has an inhibitory power with a moderate category (5-10 mm). This study Conclude Robusta coffee alkaloid and flavonoid compounds concentrations of 0.39%, 0.78%, 1.56% have the potential to inhibit the growth of porphyromonas gingivalis bacteria statistically meaningfully (ANOVA, p<0.05).
Keyword: Robusta Coffee, Porphyromonas gingivalis, periodontitis, Gel, Bacteria
I. INTRODUCTION
According to the Regulation of the Minister of Health Number 89 of 2015 concerning dental and oral health efforts, dental and oral health is a healthy state of hard tissue and soft tissues of teeth.[1] By The Global Burden of Disease Study 2016 health problems experienced by almost half of the psyche population. periodontal disease affects approximately 20-50% of the population worldwide.[2]
Periodontal disease ranks eleventh most common in the world [3]. The results of Basic Health Research (Riskesdas) in 2018 showed that Indonesians who have dental and oral health problems are 57.6% of the total 267 million people, the