Anutaila Nasya and Varunadi Ghrita in Dushta Pratishyaya (Chronic Sinusitis): A Three-Group Clinical Study

Background: Dushta Pratishyaya is described in Ayurveda as a chronic or persistent form of Pratishyaya and was correlated in the source thesis with chronic sinusitis. The thesis evaluated Anutaila Nasya, oral Varunadi Ghrita, and their combined use.
Objective: To assess the clinical response to Anutaila Nasya and Varunadi Ghrita, administered separately and together, in patients diagnosed with Dushta Pratishyaya.
Methods: This three-group clinical study was conducted among patients attending the Department of Shalya–Shalakya, IPGT&R, Gujarat Ayurved University, Jamnagar. Forty-six patients were registered and described as randomly allocated: Group A received Anutaila Marsha Nasya (16 registered; 10 completed), Group V received oral Varunadi Ghrita (15 registered; 10 completed), and Group C received both treatments (15 registered; 12 completed). Anutaila was administered at 8–10 drops per nostril during each treatment sitting for 7 days, across three sittings separated by 7-day gaps. Varunadi Ghrita was given orally at 10 g twice daily after food for one month with warm water. A one-month follow-up was undertaken. Symptoms, sinus palpation, transillumination, radiological findings and selected laboratory parameters were assessed.
Results: The thesis reports improvement in multiple symptoms in all three groups. In Group A, reported reductions included postnasal drip (85.84%), halitosis (84.40%), heaviness in the head (70.59%) and headache (60.86%). In Group V, reported reductions included headache (77.27%), anorexia (75%) and loss of smell (63.63%). In Group C, reported reductions included nasal obstruction (63.63%), nasal discharge (65.53%), headache (76.80%), postnasal drip (79.90%) and halitosis (82.35%). The thesis reports no statistically significant between-group advantage of combined treatment over Nasya for individual symptoms; comparisons with Varunadi Ghrita alone reportedly favoured combined treatment for postnasal drip and heaviness in the head (both p<0.05). These are historical thesis-reported values; raw participant-level data were not available for independent recalculation.
Conclusion: The original thesis records symptom improvement across all three treatment groups and suggests that combined treatment may be beneficial for selected outcomes. However, incomplete reporting of attrition, allocation methods, raw outcome data and ethics documentation limits firm comparative conclusions. The findings should be interpreted as exploratory and require confirmation in a rigorously reported study.

Dushta Pratishyaya; chronic sinusitis; Anutaila; Nasya; Varunadi Ghrita; Ayurveda; clinical study

1. The thesis contains a numbered bibliography and classical-text citations, but the article-level reference list must be checked against the journal’s reference style and the cited works. The available source identifies, among others: [Google Scholar] [Crossref]

2. Sushruta. Sushruta Samhita, Dalhana commentary, Nibandhasangraha. Chowkhambha Orientalia, Varanasi, 2002. Relevant sections include Uttara Tantra, chapters 19 and 24. [Google Scholar] [Crossref]

3. Vagbhata. Ashtanga Hridaya, Sarvanga Sundara commentary by Arunadatta. Choukhambha Krishna Das Academy, Varanasi, 2000. Relevant sections include Sutrasthana 15 and 20, and Uttarasthana 19–20. [Google Scholar] [Crossref]

4. Dhingra PL. Diseases of Ear, Nose and Throat. 2nd ed. Churchill Livingstone; 1998. [Google Scholar] [Crossref]

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