Basal Cell Carcinoma of the Left Nasal Wall: A Case Report and Review of Clinical Management

Among all the cutaneous malignancy basal cell carcinoma (BCC) is the most prevalent, mainly affecting sun-exposed regions of head and neck. Nasal involvement presents significant reconstructive and cosmetic challenges because of complex anatomical as well as aesthetic prominence. Hereby, we are reporting a his to pathologically confirmed case of fibroepitheliomatous variety of basal cell carcinoma involving left nasal wall in a 70year old male presenting with a slowly enlarging ulcero -proliferative lesion associated with intermittent bleeding. Wide local excision with adequate margins followed by local flap reconstruction achieved satisfactory oncologic and cosmetic outcomes. This case highlights the importance of early diagnosis, histopathological confirmation, and appropriate surgical management in preventing local tissue destruction and recurrence.

Basal cell carcinoma; Nasal wall; Cutaneous malignancy; Wide local excision

1. Cameron MC, Lee E, Hibler BP, Barker CA, Mori S, Cordova M, et al. Basal cell carcinoma: Epidemiology; pathophysiology; clinical and histological subtypes; and disease associations. J Am Acad Dermatol. 2019;80(2):303-17. [Google Scholar] [Crossref]

2. Scrivener Y, Grosshans E, Cribier B. Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol. 2002;147(1):41-7. [Google Scholar] [Crossref]

3. Leiter U, Keim U, Garbe C. Epidemiology of skin cancer: Update 2019. Adv Exp Med Biol. 2020;1268:123-39. [Google Scholar] [Crossref]

4. Marzuka AG, Book SE. Basal cell carcinoma: Pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management. Yale J Biol Med. 2015;88(2):167-79. [Google Scholar] [Crossref]

5. Trakatelli M, Morton C, Nagore E, Ulrich C, Del Marmol V, Peris K, et al. Update of the European guidelines for basal cell carcinoma management. Eur J Dermatol. 2014;24(3):312-29. [Google Scholar] [Crossref]

6. Bichakjian CK, Olencki T, Alam M, Andersen JS, Berg D, Bowen GM, et al. Basal cell skin cancer, version 1.2016. J Natl Compr Canc Netw. 2016;14(5):574-97. [Google Scholar] [Crossref]

7. Kauvar AN, Cronin T Jr, Roenigk R, Hruza G, Bennett R. Consensus for nonmelanoma skin cancer treatment: Basal cell carcinoma. Dermatol Surg. 2015;41(5):550-71. [Google Scholar] [Crossref]

8. Rubin AI, Chen EH, Ratner D. Basal-cell carcinoma. N Engl J Med. 2005;353(21):2262-9. [Google Scholar] [Crossref]

9. Cook JL, Zitelli JA. Mohs micrographic surgery: A cost analysis. J Am Acad Dermatol. 1998;39(5 Pt 1):698-703. [Google Scholar] [Crossref]

10. Weedon D. Weedon’s Skin Pathology. 4th ed. London: Churchill Livingstone Elsevier; 2015. [Google Scholar] [Crossref]

• Emerging Biologic Therapies in Autoimmune Diseases: Focus on Pemphigus Vulgaris, Generalized Myasthenia Gravis, and Psoriasis
• Monosodium Glutamate (MSG) Promotes the Contraction of Duodenal Visceral Smooth Muscle Ex Vivo in Rat
• Genotypic and Phenotypic Detection of Multidrug-Resistant Mycobacterium Tuberculosis among HIV Patients Attending Tuberculosis Reference Centres in Northwest, Nigeria
• Pleomorphic Adenoma of the Accessory Salivary Glands of the Nasopharynx: A Rare Location – Case Report and Literature Review
• Experiences of Medical Social Workers on Family Dynamics and Hospitalisation of Patients with Chronic Health Conditions at University College Hospital, Ibadan