Myomectomy in Pregnancy- A Safe Mode of Therapy. Case Discussion

Uterine leiomyoma (Fibroids) that occurs in pregnant women, on occasion, undergoes degeneration and causes sharp pain. Analgesics and a number of home remedies, including local soothing measures, are the recommended form of treatment. Surgery is generally avoided. However, for those women, the pain is persistent, and surgical removal is the only option.
We reported a Case of a pregnant woman who presented at thirteen weeks’ gestation with abdominal pain due to a degenerative fibroid. She was initially managed with analgesics and some home measures. The pain persisted, and thus, resorted to surgical management at the fifteenth week of gestation. Three leiomyomas were removed. All showed degenerative changes. The blood loss was 100 ml. This is the third case we performed, all with satisfactory outcomes. The pregnancy is progressing well now at thirty weeks of gestation. We also analyze literature reviews involving a significant number of articles and cases. All these revealed a similar pattern in the presentation, surgical management, and histology reports. Complications were minimal. No maternal death was reported. Pregnancy outcome was satisfactory.

Therefore, myomectomy in pregnancy should become a routine form of management in cases that present with the complication of pain, not relieved by analgesics and other measures.

Uterine Leiomyoma, fibroids, pregnancy, myomectomy.

1. Barjon K, Kahn J, Singh M. Uterine Leiomyomata. [Updated 2025 May 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK546680/ [Google Scholar] [Crossref]

2. Kyriaki Spyropoulou, Ioannis Kosmas, Ioannis Tsakiridis, Apostolos Mamopoulos, Ioannis Kalogiannidis, Apostolos Athanasiadis, Alexandros Daponte, Themistoklis Dagklis, (2020). Myomectomy during pregnancy: A systematic review. European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 254, ,Pages 15-24,ISSN 0301-2115, https://doi.org/10.1016/j.ejogrb.2020.08.018 [Google Scholar] [Crossref]

3. Amber, Sofia et al. (2025) Fibroids in Pregnancy: A Case Series. Cureus vol. 17,7 e87577. 9, doi:10.7759/cureus.87577 [Google Scholar] [Crossref]

4. Bubmann, Jonas et al. (2025). Review on Symptomatic pedunculated leiomyomas in pregnancy with special consideration of an example case. Archives of gynecology and obstetrics vol. 311,6 1543-1552. doi:10.1007/s00404-024-07840-4 [Google Scholar] [Crossref]

5. Loverro, Giuseppe et al. (2021). Myomectomy during pregnancy: an obstetric overview. Minerva obstetrics and gynecology vol. 73,5: 646-653. doi:10.23736/S2724-606X.21.04676-5 [Google Scholar] [Crossref]

6. Karunakaran KE, Mangalanathan V. (2009). Myomectomy in Pregnancy- an inevitable Option. A case presentation and discussion. Batticaloa Medical Journal Vol. 5 [Google Scholar] [Crossref]

7. Karunakaran KE. (2018). Fibroids and Pregnancy; Is surgical management a feasible option? Theme seminar presentation at the 51st Annual Scientific Sessions of the Sri Lanka College of Obstetricians & Gynaecologists. Sri Lanka Journal of Obstetrics & Gynaecology, Vol. 40, Suppl.1. P-7 [Google Scholar] [Crossref]

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