A Review on Aristolochia Bracteolata for Management of Lichenification (Pandri Thol Kuttam)
Authors
UG scholar, Nandha Siddha Medical College and Hospital, Erode -52 (India)
UG scholar, Nandha Siddha Medical College and Hospital, Erode -52 (India)
UG scholar, Nandha Siddha Medical College and Hospital, Erode -52 (India)
Guide, Assistant professor, Department of Research Methodology, Nandha Siddha Medical College and Hospital, Erode – 52 (India)
Article Information
DOI: 10.51244/IJRSI.2026.13020064
Subject Category: Pharmacology
Volume/Issue: 13/2 | Page No: 743-747
Publication Timeline
Submitted: 2026-02-09
Accepted: 2026-02-14
Published: 2026-02-28
Abstract
Lichenification is a chronic dermatological condition characterized by epidermal hyperkeratosis, persistent pruritus, and skin thickening, commonly resulting from prolonged scratching and inflammation. Aristolochia bracteolata, a traditionally used medicinal plant in Siddha medicine, exhibits diverse pharmacological properties that may contribute to the management and reversal of lichenified skin. The plant contains bioactive constituents such as flavonoids, alkaloids, phenolic compounds, and terpenoids , which are known to exert anti-inflammatory, anti-pruritic, antioxidant, antimicrobial, and wound-healing effects. This review aims to integrate Siddha medicinal concepts with contemporary scientific evidence to evaluate the therapeutic potential of A. bracteolata in lichenification . Although preliminary findings are promising, further experimental and clinical studies are required to establish its long-term safety and therapeutic efficacy.
Keywords
Aristolochia bracteolate, Chronic dermatitis, Lichenification, Siddha medicine
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References
1. 1.Abiraja R, Thiruthani M, Rajarajeshwari A. Describing the importance of Aristolochia bracteolata on snake bites – a review study. J Tradit Integr Med. 2019;2(4):164–176 [Google Scholar] [Crossref]
2. Shanmukavelu M. ∙ Siddha Maruthuva Noinadal Noimuthal Nadal Thirattu, Part 1Tamilnadu Govt. Siddha Medical Board, Chennai [Google Scholar] [Crossref]
3. Mathew LS, Mtewa AG, Ajayi CO, Deyno S, Weisheit A, Tolo CU, Deng AL, Ogwang PE. Ethnopharmacology, pharmacology and phytochemistry of Aristolochia bracteolata Lam: a review of an antimalarial plant. East Afr Sci. 2020;2(1):22–28. doi:10.24248/EASci-D-19-00011. [Google Scholar] [Crossref]
4. WHO international standard terminologies on Siddha medicine. Geneva: World Health Organization; 2022. Licence: CC BY-NC-SA3.0 IGO. [Google Scholar] [Crossref]
5. Aboobacker S, Harris BW, Limaiem F. Lichenification. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan [Google Scholar] [Crossref]
6. Girija DM, Kalachaveedu M, Subbarayan R, Jenifer P, Rao SR. Aristolochia bracteolata enhances wound healing in vitro through anti-inflammatory and proliferative effect on human dermal fibroblasts and keratinocytes. Pharmacogn J. 2017;9(6 Suppl):S129–S136. doi:10.5530/pj.2017.6s.169. [Google Scholar] [Crossref]
7. Murugesan Mudhalair. Gunapadam Mooligai. Department of Indian Medicine and Homeopathy, Tamil Nadu. [Google Scholar] [Crossref]
8. Nandhini DU, Rajasekar M, Venmathi T. A review on worm killer: Aristolochia bracteolata. J Pharmacogn Phytochem. 2017;6(2):6–9. [Google Scholar] [Crossref]
9. Ganesan R, Thangavel S, Ramasamy M. Anti-inflammatory activity of Aristolochia bracteolata Lam. in experimental animal models. J Ethnopharmacol. 2015;162:234-240. [Google Scholar] [Crossref]
10. Al-Snafi AE. The pharmacological importance of Aristolochia bracteolata – A review. Int J Biol Pharm Sci Rev. 2019;8(1):120-132. [Google Scholar] [Crossref]
11. Sharma N, Singh A, Patel DK. Dermatological and therapeutic potential of Aristolochia species: A pharmacognostic review. Pharmacogn Rev. 2014;8(16):112-118. [Google Scholar] [Crossref]
12. Ravi V, Saleem TSM, Patel SS, Raamamurthy J. Anti-fibrotic and wound healing activity of Aristolochia bracteolata in experimental models. Anc Sci Life. 2011;31(1):24-30. [Google Scholar] [Crossref]
13. 13.Kumar S, Pandey AK, Singh A. Antimicrobial activity of Aristolochia bracteolata against pathogenic microorganisms. Asian Pac J Trop Biomed. 2012;2(4):S1965-S1968. [Google Scholar] [Crossref]
14. Basha SK, Prasad YR, Kumar PS. Evaluation of wound healing activity of Aristolochia bracteolata Lam. in rats. Int J Pharm Res. 2017;9(3):45-50. [Google Scholar] [Crossref]
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