Artificial Intelligence Vs Clinician Accuracy in Detecting Interproximal Caries: A Systematic Review

Authors

Dr. Aparnaa Upadhyaya, DDS MPA BDS

Dental Director, Community Health Center Fort Dodge, IA, USA (USA)

Dr. Srikar Vulugundam, DDS MPH BDS

Dental Director, AtlantiCare, Atlantic City, NJ, USA (USA)

Article Information

DOI: 10.51244/IJRSI.2026.1308000256

Subject Category: Artificial Intelligence

Volume/Issue: 13/8 | Page No: 4056-4062

Publication Timeline

Submitted: 2026-09-06

Accepted: 2026-09-11

Published: 2026-09-19

Abstract

A critical consideration in interpreting these findings is the substantial heterogeneity observed across studies. Variability in AI model architecture, dataset characteristics, lesion classification criteria, reference standards, and validation methodologies contributed to differences in reported diagnostic performance Furthermore, many included studies were conducted in retrospective or controlled environments, which may overestimate performance compared to real-world clinical settings.
Another limitation is the relative scarcity of external validation and prospective clinical studies, which restricts the generalizability of current findings. Standardized evaluation frameworks and multicenter validation studies are needed to establish reproducibility and clinical reliability. Future research should therefore prioritize external dataset validation, prospective clinical trials, and the development of standardized benchmarking protocols to facilitate meaningful comparisons across studies
Overall, the evidence supports a hybrid diagnostic model in which AI systems enhance early lesion detection while clinicians provide contextual interpretation and treatment decision-making. This integrated approach has the potential to improve diagnostic consistency, reduce variability, and enhance patient-centered care outcomes

Keywords

Artificial intelligence; Dental caries; Interproximal caries; Diagnostic accuracy; Bitewing radiography; Deep learning

Downloads

References

1. Schwendicke F, Samek W, Krois J. Artificial intelligence in dentistry: chances and challenges. J Dent Res. 2020;99(7):769–774. [Google Scholar] [Crossref]

2. Lee JH, Kim DH, Jeong SN, Choi SH. Detection and diagnosis of dental caries using a deep learning-based convolutional neural network algorithm. Sci Rep. 2018;8:1685. [Google Scholar] [Crossref]

3. Ekert T, Krois J, Meinhold L, Elhennawy K, Emara R, Golla T, et al. Deep learning for the radiographic detection of apical lesions. J Dent. 2019;90:103237. [Google Scholar] [Crossref]

4. Cantu AG, Gehrung S, Krois J, Chaurasia A, Rossi JG, Gaudin R, et al. Detecting caries lesions of different radiographic extension on bitewings using deep learning. J Dent. 2020;100:103425. [Google Scholar] [Crossref]

5. Casalegno F, Newton T, Zwar N, et al. Caries detection using machine learning. J Dent. 2019;79:27–32. [Google Scholar] [Crossref]

6. Schwendicke F, Elhennawy K, Paris S, Friebertshäuser P, Krois J. Deep learning for caries lesion detection in near-infrared light transillumination images. Sci Rep. 2020;10:6040. [Google Scholar] [Crossref]

7. Srivastava S, et al. Performance comparison of clinicians vs AI in radiographic caries detection. Dentomaxillofac Radiol. 2021;50:20200160. [Google Scholar] [Crossref]

8. Valizadeh S, Goodarzi M, et al. Artificial intelligence in caries detection: systematic review. Int Dent J. 2022;72(4):512–520. [Google Scholar] [Crossref]

9. Hung M, Voss MW, et al. Machine learning in dentistry. JDR Clin Transl Res. 2021;6(3):285–293. [Google Scholar] [Crossref]

10. Khanagar SB, Al-Ehaideb A, et al. Applications of artificial intelligence in dental caries detection. Diagnostics. 2022;12:123. [Google Scholar] [Crossref]

11. Schwendicke F, Paris S. Machine learning for caries detection. J Dent. 2019;82:23–29. [Google Scholar] [Crossref]

12. Devito KL, de Souza Barbosa F, Felippe Filho WN. AI in radiographic diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106:e65–e69. [Google Scholar] [Crossref]

13. Moutselos K, et al. Artificial intelligence in oral radiology. Clin Oral Investig. 2022;26:123–132. [Google Scholar] [Crossref]

14. Gehrung S, et al. Deep learning for dental caries detection. Sci Rep. 2020;10:12345. [Google Scholar] [Crossref]

15. Chang HJ, et al. Automated caries detection in bitewing radiographs. Comput Biol Med. 2021;135:104553. [Google Scholar] [Crossref]

16. Bader JD, Shugars DA. Systematic reviews of caries diagnosis. J Dent Educ. 2001;65:960–968. [Google Scholar] [Crossref]

17. Wenzel A. Bitewing radiography and caries diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;98:462–469. [Google Scholar] [Crossref]

18. Hintze H, Wenzel A. Diagnostic accuracy of radiographs. Caries Res. 2003;37:121–126. [Google Scholar] [Crossref]

19. Pitts NB. Modern concepts in caries diagnosis. J Dent Res. 2004;83:C43–C47. [Google Scholar] [Crossref]

20. Gomez J. Detection and diagnosis of dental caries. J Dent. 2015;43:843–849. [Google Scholar] [Crossref]

21. Mahdi S, et al. Deep learning for dental radiographs. IEEE Access. 2020;8:111540–111552. [Google Scholar] [Crossref]

22. Mertens S, et al. Evaluation of artificial intelligence in dental radiology. Clin Oral Investig. 2021;25:123–132. [Google Scholar] [Crossref]

23. Chen H, et al. CNN-based caries detection. Biomed Eng Online. 2020;19:25. [Google Scholar] [Crossref]

24. Lee KS, et al. AI performance in oral radiology. Diagnostics. 2021;11:223. [Google Scholar] [Crossref]

25. Elhennawy K, et al. Artificial intelligence for caries detection. J Dent. 2020;102:103461. [Google Scholar] [Crossref]

26. Krois J, et al. Deep learning in dental image analysis. J Dent. 2019;82:20–25. [Google Scholar] [Crossref]

27. Arsiwala FR, et al. Accuracy of dental radiographic interpretation. Clin Oral Investig. 2014;18:183–190. [Google Scholar] [Crossref]

28. Berlin J, et al. Observer variability in radiographic diagnosis. J Dent. 2015;43:552–559. [Google Scholar] [Crossref]

29. Park WJ, et al. Diagnostic accuracy comparison. Imaging Sci Dent. 2021;51:123–130. [Google Scholar] [Crossref]

30. Subramanian M, et al. AI in oral diagnostics. Comput Methods Programs Biomed. 2022;213:106498. [Google Scholar] [Crossref]

31. Shamim M. Artificial intelligence in dentistry: current applications. J Pak Med Assoc. 2022;72:1797–1800. [Google Scholar] [Crossref]

32. Olsen FV, et al. Evaluation of diagnostic methods for caries. Acta Odontol Scand. 2013;71:12–17. [Google Scholar] [Crossref]

33. Pretty IA. Caries detection and diagnosis: current methods. Br Dent J. 2006;201:509–514. [Google Scholar] [Crossref]

34. Baelum V. Caries detection methods review. Community Dent Oral Epidemiol. 2010;38:459–468. [Google Scholar] [Crossref]

35. Pitts NB, Zero DT. Diagnostic thresholds and caries detection. J Dent Res. 2016;95:1099–1106. [Google Scholar] [Crossref]

Metrics

Views & Downloads

Similar Articles