Impact of Rigid Endoscopy on the Diagnosis and Treatment of Vocal Fold Leukoplakia

Background: Vocal fold leukoplakia is the most prevalent premalignant lesion of the larynx and presents heterogeneous biological behavior. Objective: To clinically present surgically treated vocal fold leukoplakia and evaluate the impact of transoperative rigid endoscopy on diagnosis and treatment. Methods: A transversal 30-year comparative study with and without rigid endoscopy was conducted. Results: Rigid endoscopy significantly improved intraoperative diagnostic accuracy and lesion detection. Conclusion: Rigid endoscopy is an indispensable tool for microsurgical treatment of vocal fold leukoplakia.

Vocal fold leukoplakia; Rigid endoscopy; Laryngeal microsurgery; Premalignant lesions

1. Rubinstein M, Fine EL, Sepehr A, et al. Optical coherence tomography of the larynx. J Otolaryngol Head Neck Surg. 2010;39(2):150–156. [Google Scholar] [Crossref]

2. Dedivitis RA, Pfuetzenreiter EG Jr, Guimarães AV. Contact endoscopy of the larynx. Acta Otorhinolaryngol Ital. 2009;29(1):16–20. [Google Scholar] [Crossref]

3. Setton ARF, D’Avila JS, et al. Variant of the laryngeal microsurgery technique. Int Arch Otorhinolaryngol. 2019;23(1):18–24. [Google Scholar] [Crossref]

4. Arens C, Piazza C, et al. Vascular changes in vocal fold lesions. Eur Arch Otorhinolaryngol. 2016;273(5):1207–1214. [Google Scholar] [Crossref]

5. Parker NP. Vocal fold leukoplakia: incidence and management. Curr Opin Otolaryngol Head Neck Surg. 2017;25(6):464–468. [Google Scholar] [Crossref]

6. Chen M, Cheng L, et al. Nonsurgical treatment for vocal fold leukoplakia. Biomed Res Int. 2017;2017:6958250. [Google Scholar] [Crossref]

7. Li CJ, Chen M, et al. Treatment experience with vocal fold leukoplakia. J Laryngol Otol. 2024;138(4):461–465. [Google Scholar] [Crossref]

8. Klimza H, et al. Vocal fold leukoplakia recurrence risk model. Sci Rep. 2024;14:266. [Google Scholar] [Crossref]

9. Koss SL, et al. Serial in-office laser treatment of vocal fold leukoplakia. Laryngoscope. 2017;127(7):1644–1651. [Google Scholar] [Crossref]

10. Chen M, Li C, et al. Morphological classification for vocal fold leukoplakia. Braz J Otorhinolaryngol. 2019;85(5):588–596. [Google Scholar] [Crossref]

11. D’Avila D, D’Avila J, et al. Premalignant laryngeal lesions: twenty-year experience. Int Arch Otorhinolaryngol. 2014;18(4):352–356. [Google Scholar] [Crossref]

12. D’Avila JA, et al. Vocal Fold Leukoplakia – 30 Years of Experience. Annals Otolaryngology and Rhinology. 2024;11(4):1340. [Google Scholar] [Crossref]

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