Pharmacological Screening of Moringa Oleifera : In Vitro Anti-Inflammatory and Antimicrobial Activities
Authors
Students, B. Pharmacy, Sri Vasavi Institute of Pharmaceutical Sciences, Pedatadepalli, Tadepalligudem, Andhra Pradesh (India)
Students, B. Pharmacy, Sri Vasavi Institute of Pharmaceutical Sciences, Pedatadepalli, Tadepalligudem, Andhra Pradesh (India)
Students, B. Pharmacy, Sri Vasavi Institute of Pharmaceutical Sciences, Pedatadepalli, Tadepalligudem, Andhra Pradesh (India)
Associate Professor, Department of pharmacology, Sri Vasavi Institute of Pharmaceutical Sciences, Pedatadepalli, Tadepalligudem, Andhra Pradesh (India)
Professor and HOD, Department of pharmacology, Sri Vasavi Institute of Pharmaceutical Sciences, Pedatadepalli, Tadepalligudem, Andhra Pradesh (India)
Professor & Principal, Sri Vasavi Institute of Pharmaceutical sciences, Pedatadepalli, Tadepalligudem, Andhra Pradesh (India)
Article Information
DOI: 10.51244/IJRSI.2026.1304000243
Subject Category: Pharmacology
Volume/Issue: 13/4 | Page No: 2848-2865
Publication Timeline
Submitted: 2026-04-22
Accepted: 2026-04-28
Published: 2026-05-19
Abstract
In Ayurveda, the traditional medicinal plant Moringa Oleifera—also known as horse radish tree is highly regarded for its healing qualities. This study aims to evaluate moringa oleifera extracts' antibacterial and anti-inflammatory qualities in vitro. The anti-inflammatory potential was assessed using the membrane stabilizing and protein denaturation methods. The antibacterial effectiveness against particular strains of bacteria and fungus was examined using the agar well diffusion method. Initial phytochemical testing revealed the presence of flavonoids, alkaloids, phenolics, and terpenoids; these substances might be in charge of the biological activities found. The extracts demonstrated significant antioxidant activity in a dose-dependent manner. The organism's significant anti-inflammatory qualities supported its traditional use in treating inflammatory illnesses. Additionally, the extracts demonstrated strong antifungal and antibacterial activity towards common strains of fungus and both Gram-positive and Gram-negative bacteria. Since it is used to boost a woman's milk production and is occasionally recommended for anemia, it is referred to as "mother's best friend" in the Philippines. Examining the antibacterial and anti-inflammatory qualities of several Moringa oleifera leaf extracts in vitro was the aim of the present one study.
Keywords
Anti-bacterial, Anti-inflammatory, Phenolic compounds
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