CO-INFECTION OF HUMAN IMMUNO-DEFICIENCY VIRUS HIV AND VIRAL HEPATITIS (B AND OR C) AMONG PEOPLE LIVING WITH HIV IN TARABA STATE

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CO-INFECTION OF HUMAN IMMUNO-DEFICIENCY VIRUS HIV AND VIRAL HEPATITIS (B AND OR C) AMONG PEOPLE LIVING WITH HIV IN TARABA STATE

 DanjumaKamlenAdda.1, Obed Tiwah John1,2*AbdulhafizLamiya1
1Center For Initiative and Development Taraba, Nigeria
2Department of Statistics and Operations Research, ModibboAdama University of Technology, Yola, Adamawa State, Nigeria
*Corresponding author: Obed Tiwah John, 

 

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Abstract
Co-infection is a phenomenon in which a person acquires multiple infection concurrently. Co-infections of HIV with hepatitis B and or hepatitis C (HCV) virus(es) among others, are major public health problems. In Nigeria, there is a limited knowledge on viral hepatitis amongst at-risk populations (PLHIV). Taraba state is ranked as the state with the highest rate of both hepatitis B and C infections. Thus, this study sought to seek for causes and effects of relationship from the three groups of viruses namely; Hepatitis B virus, Hepatitis C virus and Human immunodeficiency virus as it affects human beings with specific objectives of determining the prevalence and co-infections of the viruses amongst people living with HIV (PLHIV) in federal medical center Jalingo (FMCJ). A cross sectional study was conducted among 237 PLHIV in FMCJ of which blood samples as well as demographic data were obtained after the mandatory pretest counselling with informed consent from the client. All samples were analyzed for hepatitis B surface antigen (HBsAg) and hepatitis C antibodies using rapid diagnostic test kits. Data were entered into Microsoft Excel and SPSS version 25 of which reliability and validity test were checked using Alpha Cronbach. Out of the subjects (PLHIV) sampled, 37 (15.6%) subjects had serum samples positive for HBsAg, whilst 38 (16%) subjects had samples positive for anti-HCV. Four subjects were positive for both HBV and HCV (1.7%). There was no statistical significant association between HBV and HCV Positive cases. The prevalence of the triple infection (HIV + HCV + HBV) was 4(1.7%) of which all occurred among female PLHIV. The prevalence of both HBV and HCV infection were high among female PLHIV than Male PLHIV that is 30(12.7%) against 7(3%) for HBV and 32(13.5%) against 6(2.5%) for HCV respectively. This study reported high prevalence of hepatotropic viruses (HBV and HCV) and coinfections among PLHIV in FMCJ. Findings from this study are of great public health concern due to the fatality rate associated with the triple infection. Thus, Screening for these viruses among HIV/AIDS patients is advocated and recommended as this will allow for early detection and proper management.
Keywords: Coinfection,Hepatitis B Virus,Hepatitis C Virus,Human Immuno-deficiency Virus