Development of Novel Topical Formulations for Anti-aging Effect
- August 5, 2018
- Posted by: RSIS
- Category: Pharmacy
International Journal of Research and Scientific Innovation (IJRSI) | Volume V, Issue VII, July 2018 | ISSN 2321–2705
Development of Novel Topical Formulations for Anti-aging Effect
Dr. Meenal M Rane, Dr. Amrita Bajaj, Kapil Waghela
SVKMs Dr. Bhanuben Nanavati College of Pharmacy, Mithibai Campus, Vile Parle, Mumbai, Maharashtra, India
Abstract:-There is increase in demand for cosmetics which have anti-ageing properties as majority of the population is concentrating on personal care and maintenance of skin . Different strategies are used to enhance the efficacy of dermatological delivery systems. Several anti-ageing therapies are used by people, but these therapies are associated with several side effects which limit their applicability in the market. The present article describes the novel trends in treatment of ageing. This article focuses on the multiple uses of DL α Tocopheryl acetate in the treatment of ageing, wrinkles and its effect on moisture retention, elasticity and fatigue of the skin.
Key Words:- Anti-ageing, Nanoemulsions, Nanoemulsion based sprays and Nanogels, Novel delivery systems for cosmetics.
Key Message: Novel Drug Delivery Systems are emerging to provide more beneficial results than the conventional formulations This research highlights the use of novel delivery systems in cosmetics, analyzing new approaches for obtaining sophisticated cosmetic products and examining the same. Advances in basic research on the antioxidant activity, mechanism of action, penetration and photoprotection of vitamin E in human skin have led to the development of numerous new formulations for use in cosmetics and skin care products.
I. INTRODUCTION
Topical drug delivery systems have the major advantages as they bypass the first pass metabolism and avoid the risks and inconveniencies of intravenous therapy. Topical formulations increase the patient compliance. Topical drug delivery systems include two basic types of products i.e. external topicals which are spread on cutaneous tissue or sprayed (gels, emulgels, lotions, etc) and internal topicals are those which are applied to mucous membrane orally, vaginally or for rectal use (solutions, drops, etc).
