Haematological Profile of Diabetes and Non-Diabetes Patients in Abuja, Nigeria

International Journal of Research and Scientific Innovation (IJRSI) | Volume VI, Issue V, May 2019 | ISSN 2321–2705

Haematological Profile of Diabetes and Non-Diabetes Patients in Abuja, Nigeria

Lawrence Chinaemelu Umeji^1*, Abiodun Olaiya Paul², Sanni Olaniyi Felix³, Charity Nkem Umeji⁴, Abiodun Abiola Folake⁵, Okeke Ndubisi Chrisitian¹, Nicholas Innocent Eigege¹, Chisara Sylvestina Okolo¹

¹Defence Reference Laboratory, Asokoro, Abuja, Nigeria
²Department of National Integrated Specimen Referral Network, AXIOS Internationa
³Department of Global Health-WABCS, Lagos State University Teaching Hospital, Ikeja, Lagos State, Nigeria
⁴Department of Chemical Pathology, Federal Medical Centre, Jabi, Abuja, Nigeria
⁵Department of Medical Laboratory Services, General Hospital Makurdi, Nigeria
*Corresponding Author

Abstract: -Diabetes mellitus, has over the years become a very serious global public health challenge and a complex disease characterized by chronic hyperglycemia that leads to long-term macrovascular and microvascular complications.The purpose of this study is to investigate changes in some hematological parameters in patients with diabetes mellitus and compare the results with non-diabetic individuals that will serve as the control. This is a hospital-based case control study carried out within Abuja, Federal Capital of Nigeria. The Samples were processed and analyzed in the Defence Reference Laboratory, Asokoro, Abuja. Venipuncture was performed on each patient.Complete Blood Count was performed using the 2ML EDTA blood tubes using the Sysmex platform while Fasting blood sugar was performed using the 2ML Fluoride Oxalate blood tube, these assays were performed using an automated Chemistry analyser (Selectra Pro S). The data were analysed using SPSS (Statistical Package for the Social Science) for Windows version 25. No statistically significant differenc¬e between the diabetic and non-diabetic groups respecting gender, PLT CT and MCH whereas there were statistically signifi¬cant differences between the groups respecting; FBS, PCV, WBC, RBC, MCHC, and MCV (P<0.05). Only LUM (x109L) and MONO (x109L) were insignificantly different between diabetic and non-diabetic groups. This study revealed that unrecognized anemia exists in diabetic patients. The severity of anemia may be greater in subjects with retinopathy. It is suggested that the hematological parameters should be evaluated and treated periodically in diabetic patients to reduce the load, of ocular morbidity due to retinopathy.

Keywords: Diabetics, Heamatological parameter, Fasting Blood Sugar, Anaemia, Blood count

I. INTRODUCTION

Diabetes mellitus (DM) is a general term for heterogeneous disturbances of metabolism, the most common finding in diabetes is chronic hyperglycaemia. Hyperglycemia can quickly become life-threatening if it is not managed and controlled, Diabetes is a common community-based disease among Nigerians [1].

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