International Journal of Research and Innovation in Applied Science (IJRIAS) |Volume VII, Issue XI, November 2022|ISSN 2454-6194
Deducing the Relaxation Times of Some Polar Solvents Using Cole-Cole Relaxation Model
Musa N., Kalip A.* and Udunenwu B.C.
Department of Applied Physics, Kaduna Polytechnic, Kaduna, Nigeria
*Corresponding author
A study of the relaxation times of some polar solvents was carried out using the Cole-Cole relaxation model. The solvents; Methanol, Ethanol, Butan-1-ol were studied. The study was carried out within a frequency range of 100kHz and 50MHz and a temperature range of 100C and 500C. The following relaxation times: 0.09273 ns, 0.04073 ns, 0.03138 ns, 0.02082 ns and 0.01439 ns for methanol; 0.9360 ns, 0.6132 ns, 0.4031 ns, 0.2713 ns and 0.1812 ns for ethanol and 0.2385 ns, 0.1931 ns, 0.1424 ns, 0.1059 ns and 0.0796 ns for butan-1-ol at 10OC, 20OC, 30OC, 40OC and 50OC respectively were deduced using the slopes of the graphs plotted from the derived equation. The linear fit of the plotted points converged at the origin. The R2 values for each solvent under investigation, fitted perfectly. This eliminates the need for elaborate experimental analysis. As the temperature increases, the relaxation time decreased. These results can be used in drug design and synthesis at radio wave frequency range.
Keywords: Relaxation equation, polar solvents, methanol, ethanol, butan-1-ol, relaxation times
I. INTRODUCTION
Over time, scientific and technological advances have been made in the creation of materials that might resist the intricacies of today’s dynamic environment. These developments affect a variety of industries, including medicine, security, agriculture, food, medicines, paints, geosciences, and clothing.
Solvents that are polar protic and polar aprotic are frequently employed in manufacturing sectors. The understanding of dielectric characteristics is used by the food, medicinal, chemical, and pharmaceutical sectors at every stage of manufacturing. Poorly soluble medications, for instance, are a challenge in pharmaceutical formulation, thus the pharmaceutical industry continuously uses water and organic solvents in their manufacturing (Craig, 1995; Behera et al. 2010).
Since drug solubility is a key consideration in the discovery and formulation of new medications, improving dissolving characteristics is a significant challenge.
Most pharmaceutical materials are thermally sensitive such that drying them under reduced temperature or in vacuum is necessary. This necessitates a long drying time. Radio and microwaves offer an alternative and faster method for the removal of moisture (Satyendra, 2018).
Any liquid that helps a solute dissolve is a solvent. The element that is more abundant in a solution is the solvent. In daily life, water is presumably the most prevalent solvent. Organic