Potential of Saccharomyces cerevisiae to Control Stem Cancer Disease in Dragon Fruit Caused by Neoscytalidium dimiatum

Authors

Rahmad Faizan

Department of Plant Protection, Faculty of Agriculture, Universitas Andalas, Kampus Limau Manis Padang 25163, West Sumatera (Indonesia)

Darnetty

Department of Plant Protection, Faculty of Agriculture, Universitas Andalas, Kampus Limau Manis Padang 25163, West Sumatera (Indonesia)

Jumsu Trisno

Department of Plant Protection, Faculty of Agriculture, Universitas Andalas, Kampus Limau Manis Padang 25163, West Sumatera (Indonesia)

Article Information

DOI: 10.51584/IJRIAS.2026.11010019

Subject Category: Biology

Volume/Issue: 11/1 | Page No: 237-243

Publication Timeline

Submitted: 2025-12-20

Accepted: 2025-12-27

Published: 2026-01-24

Abstract

Neoscytalidium dimidiatum fungus is the cause of stem cancer disease on dragon fruit plant. This disease is a major disease of dragon fruit plants that is economically detrimental. The use of Saccharomyces cerevisiae is an environmentally friendly control alternative. This study aimed to determine the potential of S. cerevisiae in suppressing the growth of N. dimidiatum which causes dragon fruit vine cancer. The antagonistic tests of S. cerevisiae against N. dimidiatum were carried out in vitro and in vivo. The experimental design used in this research was a Completely Randomized Design (CRD) with 4 treatments and 6 replications. The treatments consisted of several different inoculation time of S. cerevisiae namely A (S. cerevisiae was inoculated 2 days after N. dimidiatum inoculation), B (S. cerevisiae was inoculated simultaneously with N. dimidiatum inoculation), C (S. cerevisiae was inoculated 2 days before N. dimidiatum inoculation) and D ( Control, without S. cerevisiae). The results of the research showed that treatment B (application of S. cerevisiae simultaneously with inoculation of N. dimidiatum ) and C (application of S. cerevisiae 2 days before inoculation of N. dimidiatum inoculation) inhibited the growth of N. dimidiatum in vitro and in vivo. The best treatment was C (the inoculation of S. cerevisiae 2 days before inoculation of N. dimidiatum with the persentage of inhibition by 57.8% and 87.88%. respectively.

Keywords

dragon fruit, hyperparasitism

Downloads

References

1. Benyagoub, M., Bel Rhlid, R., & Bélanger, R. R. (1996). Purification and characterization of new fatty acids with antibiotic activity produced by Sporothrix flocculosa. Journal of Chemical Ecology, 22(3), 405–413. [Google Scholar] [Crossref]

2. Carstens, M., Vivier, M. A., & Pretorius, I. S. (2003). The Saccharomyces cerevisiae chitinase, encoded by the CTS1-2 gene, confers antifungal activity against Botrytis cinerea to transgenic tobacco. Transgenic Research, 12(4), 497–508. [Google Scholar] [Crossref]

3. Dewi, A. L., & Soekarno, B. P. W. (2017). Insidensi Penyakit yang Disebabkan Cendawan pada Tanaman Buah Naga Merah (Hylocereus polyrhizus) di Kecamatan Cijeruk dan Leuwiliang Kabupaten Bogor [Institute Pertanian Bogor]. https://repository.ipb.ac.id/handle/123456789/90282 [Google Scholar] [Crossref]

4. Dy, K. S., Wonglom, P., Pornsuriya, C., & Sunpapao, A. (2022). Morphological, Molecular Identification and Pathogenicity of Neoscytalidium dimidiatum Causing Stem Canker of Hylocereus polyrhizus in Southern Thailand Plants, 11, 504. [Google Scholar] [Crossref]

5. Ezra, D., Liarzi, O., Gat, T., Hershcovich, M., & Dudai, M. (2013). First Report of Internal Black Rot Caused by Neoscytalidium dimidiatum on Hylocereus undatus (Pitahaya) Fruit in Israel. Plant Disease, 97(11), 1513. [Google Scholar] [Crossref]

6. Fu, S. F., Wei, J. Y., Chen, H. W., Liu, Y. Y., Lu, H. Y., & Chou, J. Y. (2015). ndole-3-acetic acid: A widespread physiological code in interactions of fungi with other organisms. Plant Signaling and Behavior, 10(8). [Google Scholar] [Crossref]

7. Jumjunidang, N., Yanda, R. P., Riska, N., & Emilda, D. (2019). Identifikasi dan Karakterisasi Penyakit Bintik Batang dan buah pada Tanaman Buah Naga (Hylocereus spp.) di Indonesia I. Jurnal Hortikultura, 29(1), 103. [Google Scholar] [Crossref]

8. Kementerian Pertanian. (2024). Buku Atap Hortikultura 2023. Direktorat Jenderal Hortikultura Kementerian Pertanian, https://hortikultura.pertanian.go.id/wp- ontent/uploads/2024/04/buku_atap_2023.pdf [Google Scholar] [Crossref]

9. Liu, Z., Shuang Du, S., Yi Ren, Y., and Liu, Y. Biocontrol ability of killer yeasts (Saccharomyces cerevisiae) isolated from wine against Colletotrichum gloeosporioides on grape. (2017) Journal of Bacic Microbiology, 58(1):60-67 [Google Scholar] [Crossref]

10. Lopes, M. R., Klein, M. N., Ferraz, L. P., da Silva, A. C., & Kupper, K. C. (2015).Saccharomyces cerevisiae: A novel and efficient biological control agent for Colletotrichum acutatum during pre-harvest. Microbiological Research, 175, 93–99. [Google Scholar] [Crossref]

11. Masyahit, M., Sijam, K., Awang, Y., & Satar, M. G. M. (2009). First report on bacterial soft rot disease on dragon fruit (Hylocereus spp.) caused by Enterobacter cloacae in Peninsular Malaysia. International Journal of Agriculture and Biology, 11(6), 659–666. [Google Scholar] [Crossref]

12. Nunes, C. A. (2012). Biological control of postharvest diseases of fruit. European Journal of Plant Pathology, 133(1), 181–196. https://doi.org/10.1007/S10658-011-9919-7 [Google Scholar] [Crossref]

13. Peja Jr, R., Ivan Marcelo Duka, I.M. and Mark Angelo Balendres, M.A. (2025).. Neoscytalidium dimidiatum, a plant killer: a review .Studies in Fungi 10, 1-9 [Google Scholar] [Crossref]

14. Personsa, K., Rainesa , J.M, and Jose M. Rodrigueza,, J.M. (2013),Antagonistic effects of Saccharomyces cerevisiae on the growth of Aspergillus flavus and Aspergillus parasiticus at varying temperatures . Mycology, 4 (1), 38–43 [Google Scholar] [Crossref]

15. Sanahuja, G., Lopez, P., & Palmateer, A. J. (2016). First Report of Neoscytalidium dimidiatum Causing Stem and Fruit Canker of Hylocereus undatus in Florida. Https://Doi.Org/10.1094/PDIS-11-15-1319-PDN, 100(7), 1499. [Google Scholar] [Crossref]

16. Shofiana, R. H., Sulistyowati, L., Muhibuddin, A., Hama, J., Tumbuhan, P., & Pertanian, F. (2015). Eksplorasi Jamur Endofit dan Khamir pada Tanaman Cengkeh (Syzygium aromaticum) serta Uji Potensi Antagonismenya terhadap Jamur Akar Putih (Rigidoporus microporus). Jurnal Hama Penyakit Tumbuhan, 3(1), 75–83. [Google Scholar] [Crossref]

17. Takahashi, L. M., Rosa, D. D., Basseto, M. A., de Souza, H. G., & Furtado, E. L. (2008). First report of Colletotrichum gloeosporioides on Hylocereus megalanthus in Brazil. Australasian Plant Disease Notes, 3(1), 96–97. [Google Scholar] [Crossref]

Metrics

Views & Downloads

Similar Articles