Efficacy of Mustadi Yapan Basti in Geriatric Care: a Randomized Controlled Trial

Background: Vruddhavastha (geriatric age, 60-100 years) is characterized by Vata dosha predominance, tissue depletion, and diminished strength. Mustadi Yapan Basti, a classical Ayurvedic formulation, is traditionally indicated for strength promotion and rejuvenation.
Objective: To evaluate the efficacy and safety of Mustadi Yapan Basti compared with Madhutailik Yapan Basti in managing geriatric symptoms.
Methods: Sixty-two patients (60-100 years) were randomized to receive either Mustadi Yapan Basti (Group A, n=31) or Madhutailik Yapan Basti (Group B, n=31) daily for 8 days, with follow-up on Day 24. Primary outcomes included strength (Bala), energy (Utsaha), breathlessness (Ayasen Shwas), and Vata symptoms. Secondary outcomes included walking time and laboratory parameters.
Results: Group A demonstrated superior improvements: Bala (96.30% vs 53.24%, p<0.01), Utsaha
(90.85% vs 51.03%, p<0.01), Ayasen Shwas (64.35% vs 41.10%, p<0.05), Vata symptoms (68.10% vs
42.55%, p<0.01), and walking time (31.79% vs 18.38%, p<0.01). Marked improvement (≥66% relief) occurred in 74.19% of Group A versus 29.03% of Group B. Significant improvements in hemoglobin (+4.24%), ESR (22.18%), and serum calcium (+6.98%) were observed in Group A. Adverse events were minimal and selflimiting (Group A: 16.13%; Group B: 38.71%).
Conclusion: Mustadi Yapan Basti is highly effective and safe for managing geriatric symptoms, demonstrating superior efficacy with sustained benefits and excellent tolerability.

Vruddhavastha, Geriatrics, Mustadi Yapan Basti, Panchakarma, Vata dosha, Randomized Controlled Trial

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