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Histological Pattern of Cervical Malignancies in South-South Nigeria.

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International Journal of Research and Scientific Innovation (IJRSI) | Volume VII, Issue IX, September 2020 | ISSN 2321–2705

Histological Pattern of Cervical Malignancies in South-South Nigeria.

 Sapira-Ordu Leesi1, Sapira Monday Komene2
1Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Alakahia, Port Harcourt.
2Department Urology, University of Port Harcourt Teaching Hospital, Port Harcourt.

IJRISS Call for paper

Abstract: Background: Cervical malignancies are common among women in the developing countries of the world. They are thought to be sexually transmitted and they contribute significantly to reproductive ill-health and mortality among women. Their histological patterns however vary with differences in their clinical characteristics and prognosis.
Objective: This was to determine the histological pattern of cervical cancers as they presented at the University of Port Harcourt Teaching Hospital (UPTH), Alakahia between 2005 and 2010.
Materials and Methods: The data was collected retrospectively from the surgical day book and the original request forms of the Anatomical Pathology Department of UPTH. All cervical biopsies and hysterectomy specimens (from which a diagnosis of malignant tumour of the cervix was made) were assessed.
Results: This showed that out of the 227 cervical biopsies and hysterectomy specimens taken over the period of study, 60 (26.43%) were malignant. The age range of the patients was 10 to 89 years with a single patient who had cervical cancer at 18 years of age. The peak age incidence was 50-59 years. Squamous cell carcinoma was the most common histological pattern, constituting 81.67% with a preponderance of large cell keratinizing squamous cell carcinoma in 43.33% of cases, large cell non-keratinizing squamous cell carcinoma in 20% and small cell non-keratinizing type in 8.33% of cases. 10% of the squamous cell carcinomas were not further classified. Adenocarcinoma and adenosquamous carcinoma were seen in 8.33% and 3.33% respectively while the rare neuroendocrine carcinoma was seen in 1.67% of cases.
Conclusion: Squamous cell carcinoma was the predominant histological type with preponderance of the large cell keratinizing variety, and the peak age incidence from this study is 50-59 years.

Key Words: Histological, pattern, cervical, malignancies, south-south, Nigeria.





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