Role of Botanical Drugs in Controlling Dengue Virus Disease

International Journal of Research and Scientific Innovation (IJRSI) | Volume V, Issue VII, July 2018 | ISSN 2321–2705

Role of Botanical Drugs in Controlling Dengue Virus Disease

 Ravindra B. Malabadi^1*, Raju K. Chalannavar^2*, Supriya S², Nityasree BR², Sowmyashree K², Neelambika T. Meti³

¹Miller Blvd NW, Edmonton, Alberta, Canada
²Department of Applied Botany, Mangalore University, Mangalagangotri-574199, Mangalore, Karnataka State, India
³Plant Biotechnology Laboratory, Rajiv Gandhi Institute of IT and Biotechnology, Bharati Vidyapeeth University, Pune-Satara Road, Katraj, Pune-411046, Maharashtra State, India

*Corresponding author: Ravindra B. Malabadi, Raju K. Chalannavar

Abstract:-Dengue is a mosquito-born viral infection which is one of the serious threats to human population and economic burden in tropical and sub-tropical region particularly in Asia. The viral infection causes flu-like symptoms and can develop into a potentially fatal form of the disease – dengue haemorrhagic fever (DHF) which eventually leads to dengue shock syndrome (DS). The severity of dengue fever is further amplified by the lack of treatment. Till today there is no treatment or medicine for controlling the dengue fever and except Dengavaxia which is not enough for the protection from infection of all the four serotypes of dengue. India has a rich diversity of herbal medicine which is used in traditional ethnomedicine. Indian rural population still depends upon herbal medicine for the treatment of various viral fevers including dengue virus disease because of its cost effectiveness and easily availability. Therefore, Indian traditional/folk medicine system known as Ayurveda plays an important role in controlling many viral infections including dengue disease. Hence new antiviral medicines of botanical origin could be easily accepted, being non-toxic and inexpensive. This review paper updated and discussed most of the published research work on the use of herbal medicine for the treatment of dengue fever which could be the primary knowledge on the anti dengue plants. These anti dengue plants could be further analyzed and studied for the future development of botanical drugs for controlling dengue viral disease.

Key words: Anti dengue plants, Ayurveda, dengue viral disease, herbal medicine, India

I. INTRODUCTION

Epidemic dengue is one of the life threatning viral infection transmitted from one person to another by the bites of infected female arthopod vector Aedes aegypti mosquitoe (Malabadi et al. 2011, 2010, 2017a, 2017b; Chaturvedi and Nagar, 2008; Murray et al. 2013). Female Aedes aegypti mosquitoe is also a major responsible vector for other viral infectious diseases like chikungunya, Zika virus, and Ebola virus diseses too (Malabadi et al. 2016a).

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