Antibacterial Activity of the Ethanolic Root Bark Extract of Plumbago zeylanica (Linn.)

International Journal of Research and Scientific Innovation (IJRSI) | Volume VI, Issue X, October 2019 | ISSN 2321–2705

Antibacterial Activity of the Ethanolic Root Bark Extract of Plumbago zeylanica (Linn.)

A. B. Ogunleye and J. O. Akinneye
Department of Biology, Federal University of Technology, Akure, Ondo State, Nigeria

Abstract: -This study was carried out to investigate the antibacterial activity of the ethanolic root bark extract of Plumbago zeylanica against seven bacteria isolated from two dumpsites in the city of Akure. Agar well diffusion method was used for this study. It was revealed that the ethanolic root bark extract of Plumbago zeylanica seems promising since it showed antibacterial activity against the tested bacteria (both Gram positive and Gram negative). From this study, it was recorded that the antibacterial activity of the extract increased with increasing concentration i.e. the concentration of 0.5g/ml showed the highest antibacterial activity against the tested bacteria. The highest zone of inhibition of 12.57mm was observed in Serratia spat the concentration of 0.5g/ml. Upon completion of this study, it is therefore recommended that more research work should be carried out on this plant in order to develop alternative antibacterial drugs for the treatment of diseases caused by bacteria.

Keywords- Antibacterial activity, Medicinal plants, dumpsites, Serratia spp, Bacteria, Plumbago zeylanica, Traditional, Ethanolic, Root bark extract.

I. INTRODUCTION

Over the past few decades, there has been much interest in natural materials as sources of new antibacterial agents. Different extracts from traditional medicinal plants have been tested. Many reports show the effectiveness of traditional herbs against microorganisms; as a result, plants have become one of the basis of modern medicine [1]. Medicinal plants are the local heritage with global importance. The world is endowed with a rich wealth of medicinal plants [2]. Medicinal plants are the main constituents of many of drugs of Indian system of medicine [3]. Natural products play an important role in drug development programmes in the pharmaceutical industry [4]. Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs have been isolated from natural sources, particularly from plants. Various medicinal plants have been used for years in daily life to treat diseases all over the world. Medicinal plants represent a rich source of antimicrobial in different countries and are a source of many potent and powerful drugs. A wide range of medicinal plant parts is used for extract as raw drugs and they possess varied medicinal properties [5].

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