Spectral and Microscopic Investigation of Betamethasone/ Cyclodextrin Covered Ag/Co/ Nanorods

Silver/cobalt/betamethasone/cyclodextrin nanoparticles are synthesized and characterized by UV-visible, fluorescence, FE-SEM, TEM, differential scanning colorimeter, FTIR, and XRD methods. Single emission was observed in α-CD and β-CD. Compared to the BEM/CD inclusion complex, a red or blue shifted absorption and fluorescence maximum was seen in Ag/BEM/β-CD and Ag/Co/BEM/β-CD nanoparticles. Nanoparticle size was measured by TEM-EDS and XRD methods. TEM images showed nanorods are formed in Ag/BEM/β-CD and Ag/Co/BEM/β-CD. Antibacterial activity results revealed that the Ag/BEM/β-CD and Ag/Co/BEM/β-CD nanomaterials show more antibacterial activity than isolated BEM drug. Further, BEM exhibits anticancer activity against the 2oh4 protein.

Betamethasone, Cyclodextrin, Inclusion complex, Silver nano, Nanorod,

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